research Exploring Pericyte and Cardiac Stem Cell Secretome Unveils New Tactics for Drug Discovery
New drugs for heart disease may be developed from molecules secreted by stem cells.
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research Eyelash Trichomegaly: Review of Congenital, Acquired, and Drug-Associated Etiologies for Elongation of the Eyelashes
The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Topical Application of Cyclosporin A Induces Rapid Remodeling of Damaged Anagen Hair Follicles in Cyclophosphamide-Administered Mice
Cyclosporin A helps damaged hair follicles regrow hair quickly.
research An Update on Drug-Induced Pigmentation
Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
research Developing Formulations for Drug Follicular Targeting: Nanoemulsions Loaded with Minoxidil and Clove Oil
Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Lessons Learned from the First Decade of Laser-Assisted Drug Delivery
Laser-assisted drug delivery has shown improved treatment outcomes for skin conditions and has potential to reduce side effects and treatment time.
research Drug-Induced Postinfantile Giant Cell Hepatitis
Certain liver diseases respond well to specific treatments and have varying risks for liver cancer.
research Selective and Rapid Determination of Tadalafil and Finasteride Using Solid Phase Extraction by High Performance Liquid Chromatography and Tandem Mass Spectrometry
Quick, selective detection of tadalafil and finasteride in human plasma developed.
research Drug Safety Evaluation of Exemestane
Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.
research Maintenance of Optimized Hair Growth from Viable Terminal Scalp Hair Follicles at Baseline with Oral Finasteride in Male Pattern Hair Loss and First Evidence of a Drug Dependency and a Post-Finasteride Rebound Effect
Finasteride helps hair growth but stopping it causes faster hair loss.
research Development and Validation of Rapid and Simultaneous Method for Determination of 12 Hair-Growth Compounds in Adulterated Products by UHPLC-MS/MS
Researchers created a reliable method to detect hair-growth substances in products.
research HHV-6A and HHV-6B in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms
The document concludes that reactivation of herpesviruses, especially HHV-6, is linked to severe symptoms and complications in drug-induced hypersensitivity syndrome.
research Chapter 14: Principles of Drug Metabolism
Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.
research Cutaneous Adverse Drug Reactions to Antibiotics: Extent of the Problem
Antibiotics often cause skin reactions, making them a major health concern.
research Drug Delivery Systems Based on Microneedles for Dermatological Diseases and Aesthetic Enhancement
Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.
research Drug Information Analysis Service: Effectiveness of Cromolyn Sodium in Treating Asthma in Children Under 2 Years Old
Cromolyn sodium's effectiveness for treating asthma in children under 2 is unclear, possibly more beneficial for older children, and further research is needed.
research Editorial: Retinoids — Dermatologists’ Drug of the Decade
Retinoids are important for treating skin conditions but should be used with caution due to serious side effects and risks during pregnancy.
research Finasteride and Sperm Concentration: Rapid Systematic Review
Finasteride appears safe for long-term sperm concentration, but more research is needed for clear conclusions.
research DrugNet: Network-Based Drug–Disease Prioritization by Integrating Heterogeneous Data
DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.
research Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances
The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
research Ablative Fractional Resurfacing in Topical Drug Delivery: An Update and Outlook
Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
research Minoxidil Is a Potential Neuroprotective Drug for Paclitaxel-Induced Peripheral Neuropathy
Minoxidil may protect nerves and improve hair quality during paclitaxel treatment.
research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Protective Effect of Korean Red Ginseng Against Chemotherapeutic Drug-Induced Premature Catagen Development Assessed With Human Hair Follicle Organ Culture Model
Korean Red Ginseng may protect against hair loss caused by chemotherapy.
research Adverse Dermatologic Effects of Cardiovascular Drug Therapy: Part III
Cardiovascular drugs can cause various skin problems, so recognizing these reactions is important.
research Comprehension Testing for Over-the-Counter Drug Labels: Goals, Methods, Target Population, and Testing Environment
The paper concludes that drug labels should be clear for all, especially for those with low literacy, and suggests aiming for high comprehension test passing rates with diverse test populations.
research Recent Advances in Drug Design and Drug Discovery for Androgen-Dependent Diseases
New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
research Evolution of Ritlecitinib Population Pharmacokinetic Models During Clinical Drug Development
Ritlecitinib shows promise as a versatile treatment for various autoimmune and inflammatory diseases.