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Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Minoxidil helps heart function but doesn't improve exercise ability and may cause complications.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Fullerenes show potential in skin care but need more safety research.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.