research Telescope Model for Coordinated Organ Morphogenesis and Stem Cell Formation
Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.
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research Degradation of Aberrant NETs by DNases as a Therapeutic Strategy for SJS/TEN
Using DNase enzymes to break down harmful NETs could be a new treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis.
research Comparison of 1064-nm Nd:YAG Picosecond Lasers Using Fractional Micro-Lens Array vs. Ablative Fractional 2940-nm Er:YAG Lasers for the Treatment of Atrophic Acne Scar in Asians: A 20-Week Prospective, Randomized, Split-Face, Controlled Trial
Both laser treatments improved acne scars similarly, but the Nd:YAG laser was safer and less painful, while the Er:YAG laser left patients slightly more satisfied.
research Epithelially Derived MPZL3 Negatively Regulates Murine and Human Sebaceous Gland Size and Sebocyte Proliferation
MPZL3 protein helps control the size of oil glands and the growth of oil-producing cells in both mice and humans.
research IL-9/IL-9R Signaling as a Novel Regulator of Human Hair Follicle Growth and Immune Privilege
IL-9/IL-9R signaling can negatively affect human hair growth and may be a target for treating hair loss conditions.
research Men's Skin Needs Energy for Proper Skin Recovery and the Combination of Compounds A and B Exhibits Strong Antioxidant and Energy-Amplifying Benefits
Compounds A and B help men's skin recover faster by reducing oxidative damage and increasing energy levels.
research Mechanical Force Activation of TGF-β Signaling Controls Hair Follicle Regression
Muscle around hair follicles controls hair loss by releasing a signal that causes cell death.
research Temporary Cell Cycle Arrest by ALRN-6924: A Novel P53-Targeting Strategy to Protect Human Scalp Hair Follicles Against Cyclophosphamide-Induced Alopecia
ALRN-6924 can protect hair follicles from chemotherapy damage by temporarily stopping cell division.
research Single-Cell RNA Sequencing Reveals POUF51 and HES3 as Regulators of the Stem Cell Population in Psoriasis
POUF51 and HES3 are key in controlling stem cell numbers in psoriasis.
research Environmental Pathobiology of Frontal Fibrosing Alopecia: A Link Between Linalool Sensitization and FFA Development
Being allergic to linalool, a common fragrance ingredient, might contribute to developing frontal fibrosing alopecia.
research Ashwagandha-Derived Exosome-Like Nanoparticles Promote Human Hair Growth Ex Vivo
Ashwagandha nanoparticles help increase hair growth.
research Epithelially Derived, Mitochondrial MPZL3 Negatively Regulates Murine and Human Hair Follicle Cycling
A protein called MPZL3 in mitochondria slows down hair growth and could be a target for treating hair growth disorders.
research Response to Ritlecitinib Treatment Based on Salt Improvement Scores in Patients With Alopecia Areata: Post Hoc Analysis of the Allegro Phase 2b/3 Study
Ritlecitinib significantly improves scalp hair regrowth in alopecia areata patients over time.
research Autophagy Controls the Protein Composition of Hair Shafts
Autophagy is important for determining the protein makeup of hair.
research Study of Long-Term 15-Day Imiquimod Treatment and Drug Intervention in Localized Psoriasiform Dermatitis Model
Long-term Imiquimod treatment causes initial skin inflammation that lessens over time, and topical corticosteroids reduce this inflammation and cytokines in a mouse model of psoriasis.
research A Combination of Honey to Repair Asian Hair from UV-A and Environmental Pollution-Induced Damage
Honey mixture improved damaged Asian hair, making it stronger, softer, and shinier.
research Epidermal Growth Factor Receptor Protects From Immune Privilege Collapse and Scarring Hair Follicle Destruction
Blocking EGFR can lead to hair loss due to inflammation and stem cell damage.
research Clinical Technique and Outcomes of Platelet-Rich Plasma Application for Treatment of Androgenic and Scarring Alopecia, Acne Scarring, Melasma, and Facial Rejuvenation: A Prospective Multicenter Study
Platelet-rich plasma treatment is generally safe and effective for hair loss, acne scars, skin discoloration, and facial rejuvenation, but deeper injections are better and multiple treatments can increase risk of side effects.
research A Quantitative Study of Desquamation in the Stratum Corneum
New method measures skin cell turnover quickly and effectively, showing turnover slows with age and responds more to treatments in older skin.
research Single-Cell Transcriptomics Reveals Distinct Molecular Programs in Folliculotropic Mycosis Fungoides
Folliculotropic mycosis fungoides has unique molecular features and cell interactions that could guide targeted therapy.
research Cross-Comparison of Inflammatory Skin Disease Transcriptomics Identifies PTEN as a Pathogenic Disease Classifier in Cutaneous Lupus Erythematosus
PTEN was identified as a specific marker for the skin disease cutaneous lupus erythematosus, and it helps increase the expression of harmful type I interferons.
research Translation-Dependent Skin Hyperplasia Promoted by Type 1/17 Inflammation in Psoriasis
Type 1/17 inflammation in psoriasis increases skin cell growth due to a molecule that could be a new treatment target.
research Prospective Study of the Metabolic Effects of Tumescent Liposuction
Tumescent liposuction reduces waist and hip size but doesn't significantly change metabolic markers, though it may slightly improve blood pressure and certain protein levels.
research Proteomic Analysis of Cultured Dermal Papilla, Dermal Sheath, and Dermal Fibroblast Cells from Female Scalp Highlights Alterations in the Cell Populations with Increasing Age
Protein analysis shows aging changes in scalp cell types from women.
research Wildfire Air Pollution and Increased Online Search Interest and Clinic Visits for Psoriasis
Wildfire air pollution is linked to more online searches and clinic visits for psoriasis in adults after a delay.
research The Relative Frequency of Small Vessel Cerebrovascular Disease and Brain Atrophy in MRI of Patients With Psoriasis
Psoriasis patients did not show more brain atrophy or small vessel disease than controls, but longer psoriasis duration was linked to more brain atrophy.
research Humoral Immune Response to COVID-19 Vaccination in Psoriasis Patients on Biologic Therapy Is Impaired Compared to Healthy Controls
Psoriasis patients on biologic therapy have a weaker immune response to COVID-19 vaccination than healthy people.
research Single-Cell RNA Sequencing of Different Fibroblast Populations Cultured from Female Scalp Reveals Significant Alterations to Transcriptional Profiles with Age
Aging changes female scalp cells, likely affecting hair health.
research Single-Cell Transcriptomic Profile of EGFR-Deficient Epidermal Compartments During Folliculitis
EGFR deficiency causes significant changes in skin cells and hair follicles.
research Comparison of Ruxolitinib and a Collagen-Targeted PTH-Based Hair Cycle Stimulant on Hair Follicle Counts and Hair Growth in the C3H/HeJ Engrafted Mouse Model of Alopecia Areata
A PTH-based treatment improved hair regrowth better than ruxolitinib in a mouse model of hair loss.