Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This article reviews new drug therapies for endocrine disorders, discussing specific treatments such as trilostane for hyperadrenocorticism and various insulins for diabetes mellitus, but it reports no new clinical findings.

This review discusses the clinical features of trichotillomania and the challenges in its diagnosis and treatment, reporting no new clinical findings while highlighting the need for specialized therapy and better therapeutic options.

This study found that pelage abnormalities in Harlequin mutant mice are linked to severe AIF deficiency and associated with altered expression of genes related to hair structure.

This review examines nanozymes as promising tools for cancer diagnosis and therapy due to their enzyme-mimicking catalytic properties and highlights their challenges, including biosafety and clinical translation, alongside potential improvements through biomimetic designs, particularly utilizing exosome-based strategies for targeted delivery to tumors.

This study found that the absence of Hif-p4h-2 in specific mouse skin cells disrupted hair follicle development, leading to hair loss due to irregular keratin formation and pathway signaling.

This study reports how the Polish-American Medical Society (ZLP Chicago) played a proactive role during the COVID-19 pandemic in the Chicago area, leading efforts in public education, support for administrative measures, and dissemination of health guidelines to the Polish community.

ZPK helps skin cells mature and may affect skin health.

This study found that the zinc transporter ZIP10 is crucial for epidermal development, as it influences the activity of p63, promoting epidermal morphogenesis.

This study found that adding pioglitazone to either spironolactone or metformin improved metabolic parameters and insulin resistance in women with PCOS, despite an increase in BMI.

Bimekizumab quickly improves psoriasis symptoms and skin at the molecular level.

Adding zinc to pyrithione zinc improves its effectiveness against scalp conditions like dandruff.

Pioglitazone may help treat lichen planopilaris, but more research is needed.

This study found that the Piezo1 ion channel reduces the efficiency of keratinocyte migration, and its inhibition in mice accelerates wound healing.

This study indicates that MPZL3 negatively regulates sebaceous gland size in mice by controlling sebocyte proliferation, with implications for disorders like acne and psoriasis.

Finasteride and GIZh-72 reduce inflammation, with GIZh-72 being more effective.

In this first-in-human study, BLZ-100, an intraoperative fluorescent imaging agent, was administered to 21 patients before skin cancer surgery and was found to be well tolerated without serious adverse effects, suggesting its potential to help distinguish cancerous from non-cancerous tissue based on fluorescence.

In this study, pioglitazone treatment in patients with lichen planopilaris showed limited success, with significant improvement seen in only a minority of cases.

In this study using mice, researchers found that the Piezo1 channel regulates metabolic changes and immune cell infiltration during skin growth under tension, with altered expression of glycolysis-related genes and increased macrophage activity observed in stretched skin.

This study shows that ZIP7 is a functional zinc transporter in mammalian cells, facilitating the movement of zinc from the Golgi apparatus to the cytoplasm.

In this study, pioglitazone treatment in insulin-resistant PCOS patients decreased relative 5alpha-reductase activity without significantly affecting cortisol levels or urinary cortisol excretion.

This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.

This historical overview commemorates Grzegorz Józef Wojciech Ziembicki, a pioneering surgical leader at Lviv General Hospital, highlighting his contributions to surgical education, innovative procedures, and anesthesia practices during his tenure from 1882 to 1915.

This study found that MPZL3 plays a crucial role in controlling sebaceous gland size and sebocyte proliferation in mice and humans, implicating its potential involvement in skin disorders like acne and psoriasis.

This review details how zinc pyrithione's anti-fungal activity makes it a successful treatment for dandruff and seborrheic dermatitis, by effectively targeting Malassezia yeast in the scalp.

This study demonstrates that MPM-FLIM multimodal imaging can effectively assess the delivery and dissolution of zinc pyrithione particles in human skin follicles using different application techniques.

This study reported that ZSYY001, a nanoparticle formulation of polymeric micellar paclitaxel, showed promising antitumor activity and was safe and well-tolerated in preclinical models and a phase I trial, without acute hypersensitivity reactions at doses up to 390 mg/m².