Antiexudative Effects of Finasteride and a New Pyrazolo[C]Pyridine Derivative GIZh-72 in Acetic Acid-Induced Experimental Peritonitis
February 2020
in “
Bulletin of Experimental Biology and Medicine
”
TLDR Finasteride and GIZh-72 reduce inflammation, with GIZh-72 being more effective.
A study conducted on rodents found that both finasteride and a new pyrazolo[C]pyridine derivative called GIZh-72 had anti-inflammatory effects in mice with induced peritonitis. GIZh-72 was found to be more effective than finasteride, indicating its potential as a therapeutic agent for peritonitis. Finasteride also had analgesic effects and enhanced the analgesic effect of morphine in rodents. The study suggests that both finasteride and GIZh-72 have potential therapeutic applications in inflammatory diseases. However, further research is needed to confirm these findings.
