Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, researchers found that the human hair follicle microbiota vary by anatomical compartment and donor age, with specific microbes like S. epidermidis potentially influencing hair follicle functions, which suggests new avenues for therapeutic targeting.

In this article, researchers link menopause to hair follicle lifecycle changes, noting that estrogen decline, metabolic shifts, genetics, and stress can contribute to hair thinning and texture variation, although effects differ among women.

In this study, pioglitazone treatment in patients with lichen planopilaris showed limited success, with significant improvement seen in only a minority of cases.

This study found that total glucosides of paeony (TGP) reduced hair loss and inflammation in alopecia areata mice by inhibiting cellular pyroptosis.

This article discusses the introduction of the term 'prepubertal pattern hair loss' to describe hair thinning in children under 10 without physical abnormalities, and reports no new clinical findings.

This study found that intramuscular injections of a PRP-derivative in healthy beagle dogs did not result in statistically significant changes in lumbar muscle tissue or IGF-1 blood concentration, suggesting the treatment may be safe at therapeutic doses.

This study suggests that the anogenital distance measure AGD_AC may moderately discriminate the presence of polycystic ovarian syndrome and could be a useful clinical tool.

This study found that mice lacking sPLA2-IIE had distinct skin abnormalities, particularly affecting hair follicles, highlighting the differing roles of sPLA2 isoforms in mouse skin.

This study found that adding pioglitazone to either spironolactone or metformin improved metabolic parameters and insulin resistance in women with PCOS, despite an increase in BMI.

This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.

This narrative review discusses the mixed and evolving evidence regarding glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and their influence on erectile dysfunction in men with type 2 diabetes and obesity, highlighting potential benefits and concerns yet to be clarified.

This study found that PGRP-S expression in mouse epidermis is specific to certain hair follicle epithelia, depending on the skin region, and can be transiently induced in flank skin hair follicle epithelium after exposure to Staphylococcus aureus, suggesting a role in environmental surveillance.

This study suggests that IGF-1, a component of human placenta hydrolysate, promotes hair growth by increasing the number and size of hair follicles in mice.

This study found that elagolix treatment did not normalize the ovulatory cycle in patients with polycystic ovarian syndrome.

This study found that selective deletion of PIKFyve kinase using a PF4 promoter in mice led to defective platelet lysosome biogenesis and a prothrombotic effect, with unexpected macrophage infiltration in multiple organs.

This article discusses Graham-Little Piccardi Lassueur Syndrome, a rare variant of Lichen planopilaris, but reports no clinical findings or results.

PGD2 stops hair growth and is higher in bald men with AGA.

This study concluded that 2-hour oral glucose tolerance tests are crucial for screening glycemic disorders in women with PCOS, as HbA1c was found to be an unsatisfactory tool for predicting glycemic disorders within this group.

This study found changes in the PGI2 pathway, especially in gene and protein expression, in diabetic mice, but did not observe PGI2-dependent vasomotor dysfunction.

In this study, PEGDE above 10,000 μg/mouse caused subcutaneous toxicity including ulceration in mice, but did not affect liver, spleen, or kidney tissues.

In this commentary, the authors discuss emerging evidence primarily from pharmacovigilance data and retrospective studies indicating a potential association between GLP-1 receptor agonists, like semaglutide and tirzepatide, and hair loss, although causality remains unproven, prompting recommendations for patient monitoring and further research.

This study found that glucagon-like peptide-1 receptor agonist therapy was independently associated with an increased incidence of non-scarring hair loss, including telogen effluvium and androgenic alopecia, in adults but not alopecia areata.

Poly-γ-glutamic acid may help reduce hair loss.

Pallister-Killian Syndrome is a complex genetic disorder requiring coordinated care and genetic counseling.

This study reports that the Swedish newborn screening program for phenylketonuria, galactosaemia, and biotinidase deficiency is effective, with high sensitivity and specificity, and lower false positive rates compared to other countries, while genetic variants impact detection and incidence patterns in Sweden.

This study found that GLP1-RAs, while not triggering significant safety signals, were reported more often for suicide, hair loss, and aspiration events compared to some other diabetes medications.

GLP-1 and GLP-1/GIP agonists may increase the risk of hair loss.