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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Finasteride's polymorphic form affects capsule quality and drug effect, requiring strict control.

Allopregnanolone changes gene expression in glioblastoma cells.

Finasteride may lower cholesterol and slow heart disease progression.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Vitamin D and its receptor are essential for hair growth, cell regulation, immune function, and heart health.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

The new gel formulation effectively delivers Finasteride for hair growth treatment without skin irritation.

Created tablet similar to Avodart using γ-cyclodextrin and solubilizers.

Errors found in identifying furosemide and finasteride polymorphs due to incomplete data.

PPAR alpha may help in hair growth and could be a target for treatment.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Innovative methods are reducing animal testing and improving biomedical research.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.