120 citations,
April 2019 in “The Journal of clinical investigation/The journal of clinical investigation” Both estrogens and androgens are important for health in both males and females.
107 citations,
March 2014 in “BoneKEy Reports” Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.
102 citations,
July 2020 in “International journal of molecular sciences” Hormones like testosterone and estrogen significantly affect hair growth and structure.
63 citations,
May 2009 in “Dermato-endocrinology” Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.
59 citations,
September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
56 citations,
August 1994 in “PubMed” Prolactin and melatonin can stimulate hair growth in Cashmere goat hair follicles, but melatonin may reduce follicle viability over time.
54 citations,
October 2010 in “Clinics in dermatology” Diet, especially dairy and high-sugar foods, can cause acne.
48 citations,
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
39 citations,
November 2021 in “Clinical Endocrinology” Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.
27 citations,
May 2002 in “The Journal of Clinical Endocrinology & Metabolism” Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.
19 citations,
March 2022 in “International Journal of Environmental Research and Public Health” Certain brain hormones and chemicals are linked to the development of Polycystic Ovary Syndrome.
15 citations,
September 2021 in “Frontiers in Endocrinology” Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.
15 citations,
April 2016 in “Hormones” Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.
15 citations,
August 2010 in “Fertility and sterility” Metformin works better for adolescent girls with PCOS who have certain genetic variations.
9 citations,
July 2018 in “Medicine” Men with vertex baldness may have a higher risk of developing prostate cancer, but more research is needed to confirm this.
8 citations,
December 2022 in “International journal of molecular sciences” Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.
7 citations,
May 2021 in “Seizure” Some antiseizure medications can cause cosmetic problems like hair loss, excessive hair growth, acne, and gum overgrowth.
7 citations,
January 1989 in “Archives of Dermatological Research” The side gland of Suncus murinus is a good model for studying human sebaceous glands.
5 citations,
September 2021 in “Dermatology Reports” Skin problems like acne and excess hair in PCOS are common and linked to being overweight.
5 citations,
June 2018 in “Journal of Diabetes, Metabolic Disorders & Control” Women with PCOS may have higher bad cholesterol and are at risk for blood sugar issues; lifestyle changes are recommended.
5 citations,
July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.
4 citations,
December 2022 in “Frontiers in Endocrinology” Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
3 citations,
May 2022 in “Clinical endocrinology” Hair steroid measurement is an effective method to diagnose and monitor CAH in developing countries.
3 citations,
November 2021 in “IntechOpen eBooks” The testes produce important hormones like testosterone and others that play key roles in male body functions.
3 citations,
November 2021 in “Stress” Girls had higher stress hormone levels during school due to social and emotional issues, while boys had higher overall hormone levels with slight changes when school started.
3 citations,
November 2019 in “Journal of the ASEAN Federation of Endocrine Societies” A 20-year-old woman with a rare form of Turner syndrome showed improvement with hormonal therapy and needs comprehensive care.
2 citations,
August 2022 in “Middle East Fertility Society Journal” The new rodent model successfully mimics non-lean human PCOS symptoms.
2 citations,
July 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Sex hormones likely don't affect atopic dermatitis in adolescents and adults.
2 citations,
July 2021 in “Annales De Dermatologie Et De Venereologie” Vulvar acne, also known as "vulvar Fordyce adenitis", is a condition causing painful bumps on the labia, and it's not always effectively treated with common acne medications, but isotretinoin has shown promise.
2 citations,
January 2017 in “Endocrinology” Testosterone and its metabolites have varied effects on different body systems, especially during puberty.