September 2025 in “Middle East Fertility Society Journal” This study found that 10.3% of female high school students in Islamabad screened positive for PCOS, with associations including irregular menstrual cycles and higher BMI among those testing positive.
December 2024 in “Archiv Euromedica” In this review, researchers reported that PCOS remains a complex condition with ongoing diagnostic and therapeutic challenges, highlighting recent innovations in diagnosis and treatment that provide alternative options for cases unresponsive to standard care.
December 2025 in “PLOS Global Public Health” This study assessed women in Bangladesh and found that those with PCOS had markedly higher rates of depression, anxiety, stress, and insomnia compared to those without the condition, with rural women showing higher anxiety and insomnia.
20 citations
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November 2019 in “International Journal of Environmental Research and Public Health” This study found that high exposure to air pollutants like SO2, NO, NO2, NOx, and PM2.5 was linked to a significantly increased risk of developing PCOS in women.
101 citations
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May 2014 in “PLOS ONE” This study found that women with polycystic ovary syndrome have an increased risk of developing depressive disorder, anxiety disorder, and sleep disorder compared to those without the syndrome.
5 citations
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January 2023 in “International Journal of Environmental Research and Public Health” This study found that women with PCOS who reported the highest levels of physical activity also reported better outcomes in BMI, mental health, and sleep quality, suggesting that enhancing motivation may improve participation in physical activity.
April 2022 in “International Journal of Health Sciences (IJHS)” This qualitative study assesses various treatment approaches for PCOS and suggests that yoga, diet, exercise, and therapies like mindfulness-based cognitive therapy may help manage symptoms from a holistic perspective.
August 2025 in “Journal of Medical and Life Science” This case-control study in Missan Province, Iraq, found that married women with PCOS had higher rates of obesity and menstrual irregularities, along with elevated testosterone, LH, and insulin levels, compared to healthy controls, highlighting significant hormonal and metabolic complications.
December 2022 in “The Indian journal of chest diseases & allied sciences” This study found that sleep disorders, especially poor sleep quality, are common in women with PCOS, suggesting the need for regular screening using specific questionnaires.
April 2016 in “Journal of The American Academy of Dermatology” This study reported that inpatient dermatology consultations at a large tertiary care center led to treatment changes in 81.9% of cases, particularly improving management of complex cutaneous conditions associated with systemic diseases.
2 citations
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September 2023 in “Journal of the American Academy of Dermatology” 4 citations
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April 2018 in “Fertility and sterility” This position statement from the Androgen Excess-Polycystic Ovary Syndrome Society highlights the need to address the overlooked behavioral and psychosocial issues like depression, anxiety, and eating disorders in women with PCOS, emphasizing the lack of adequate evidence-based treatments for these challenges.
1 citations
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March 2024 in “Türk Kadın Sağlığı ve Neonatoloji Dergisi” This study concluded that among patients with polycystic ovary syndrome at their clinic, the most common phenotype was group A, with lifestyle modification and oral contraceptives being frequently used treatments.
April 2016 in “The Journal of Sexual Medicine” This study analyzed 3,295 cases from the FDA Adverse Event Reporting System to describe demographics and reporting trends of post-finasteride syndrome, finding that most reports came from patients rather than health professionals.
October 2023 in “The Egyptian Journal of Hospital Medicine ” This review discusses the potential use of prostate specific antigen as a diagnostic marker for hyperandrogenism in polycystic ovary syndrome but reports no new clinical results and calls for further research.
16 citations
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July 2020 in “Health and Quality of Life Outcomes” This study found that health-related quality of life was significantly lower in women with polycystic ovary syndrome, especially those with the anovulatory phenotype, compared to non-PCOS controls attending a tertiary hospital.
November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” This study reported that women with polycystic ovarian syndrome are more likely to experience depression and have a poorer body image perception compared to healthy controls.
This study found no differences in psychopathic traits between women with and without polycystic ovary syndrome, challenging the proposed link between testosterone levels and psychopathy.
January 2007 in “Edward Elgar eBooks” In this study, overexpressing TSPO in the mouse hippocampal dentate gyrus led to significant anxiolytic and antidepressant-like effects, partly through increased allopregnanolone biosynthesis.
3 citations
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March 2021 in “Journal of Pediatric and Adolescent Gynecology” This study observed a higher prevalence of PCOS among adolescent girls with pilonidal disease and suggested that treating PCOS may reduce the need for PD intervention.
1 citations
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April 2022 in “Annals Academy of Medicine Singapore” This review covers the clinical features and heterogeneity of polycystic ovary syndrome and reports no new findings, emphasizing the need for further research on its complex traits and interactions.
This study found that women with PCOS, particularly those with the anovulatory phenotype, reported significantly lower physical health-related quality of life than women without PCOS at a tertiary hospital.
August 2025 in “Journal of Association of Clinical Endocrinologist and Diabetologist of Bangladesh” This article reviews the challenges in diagnosing and treating adolescent PCOS and suggests that the SPIOMET therapy could be promising, though further studies are needed.
June 2026 in “IP Indian Journal of Clinical and Experimental Dermatology” This study observed that a significant proportion of women with acne vulgaris also met the criteria for PCOS, suggesting a notable link between the two conditions.
April 2005 in “CRC Press eBooks” Excessive androgens in women with polycystic ovary syndrome can lead to excessive hair growth and hair loss, but this might not fully explain these conditions.
28 citations
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August 2009 in “Nursing for Women's Health” This review highlights that while healthcare providers are starting to diagnose polycystic ovary syndrome earlier in teens, the psychological and social needs often remain inadequately addressed.
December 2020 in “International Journal of Research in Pharmaceutical Sciences” This review analyzes the mnemonic MY PCOS, exploring diagnosis and treatment strategies for the metabolic, cosmetic, and reproductive complications of polycystic ovary syndrome, without reporting new clinical findings.
1 citations
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February 2024 in “Gynecological Endocrinology” This study found that cyclic MPA is as effective as OCPs in resuming ovulation among women with PCOS, offering a viable alternative for those who cannot or choose not to use OCPs.
3 citations
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July 2015 in “International Journal of School Health” This study found that in a sample of female adolescents in Shiraz, the most common PCOS phenotype was hyperandrogenic with polycystic ovary syndrome, warranting further investigation due to associated risks.