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The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Minoxidil needs specific structure to block lysyl hydroxylase; exploring alternatives may keep benefits without this effect.

AGD1's PH domain is essential for its role in root hair growth and polarity.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Key genes linked to immune response are upregulated in hair follicles and skin tissues in chronic discoid lupus erythematosus.

Key genes linked to immune response are highly active in lupus-affected hair follicles.

Applying the anti-cancer drug Bortezomib to skin can promote hair growth and increase hair proteins through the GATA-3 factor.

Disposable instruments could be the future of hair restoration surgery to eliminate disease risk, but they require careful preparation and proper training.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Minoxidil helps hair growth and prevents hair loss in androgenetic alopecia. It's safe and effective.

Keratins are important for skin cell health and their problems can cause diseases.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.

Enzyme purified and characterized for minoxidil sulphation in rat liver.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.