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A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

A woman was the first known case to have both polycystic ovary syndrome and autoimmune polyglandular syndrome type 2, suggesting a need to check for both conditions in similar patients.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

A new PAX9 gene mutation causes missing teeth and hair problems, but not skin or nail issues.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Hair growth is cyclic and influenced mainly by local factors.

New treatments for diabetes, central nervous system repair, and cartilage injury were found, and a way to create functional hair follicles from stem cells was developed.

The new "whisker follicle microinjection assay" can test how different biomolecules affect hair growth and color.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Low-glycemic index diets are beneficial for weight loss and satiety, but more research is needed on long-term effects and individualized approaches are recommended.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.

Bariatric surgery can cause serious mineral deficiencies, requiring better patient education and monitoring.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

FGF5 gene mutations cause long hair in domestic cats.

A woman developed swelling in her body after taking low-dose oral minoxidil for hair loss, but it resolved after stopping the medication.

A Korean boy's skin and digestive symptoms were caused by a rare genetic disorder that affects zinc absorption, and he got better with zinc supplements.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Early diagnosis and a strict gluten-free diet are crucial for children with celiac disease to improve symptoms.

Rosemary-based gel with metformin may effectively treat hair loss like minoxidil.

The document concludes that more research is needed on making and understanding biomaterial scaffolds for wound healing.