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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Skin fat helps with body temperature control and has other active roles in health.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

The conclusion is that recognizing hair growth cycles can improve the precision of dietary and health assessments from hair analysis.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Jaw wiring helps with weight loss but long-term habits are needed to keep it off.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

Metformin helps manage diabetes, PCOS, and weight in kids but needs more research for long-term safety.

Eclipta alba extract may help treat obesity by blocking fat cell formation and lowering blood lipid levels.

Blocking adenosine A2B receptor may prevent or treat hearing loss.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Fish oil improves skin health in people with diabetes and high cholesterol.

A balanced diet and healthy lifestyle help manage PCOS symptoms.

Dianabol boosts muscle growth but has serious health risks and legal issues.

Ziziphus spina-christi leaf extract lowered blood sugar and protected organs in diabetic rats.

The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.