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The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Keratins are important for skin cell health and their problems can cause diseases.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Anti-androgens, like finasteride, dutasteride, and spironolactone, may lessen the severity of COVID-19 in men, leading to fewer ICU admissions.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Phosphorylation of certain parts of the PIN3 protein is crucial for its role in plant root growth and response to gravity.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Hoxc genes control hair growth through Wnt signaling.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Red ginseng oil and its components help promote hair regrowth and could treat hair loss.

Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.

The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.

Understanding glycans and enzymes that alter them is key to controlling hair growth.

Certain essential oils can activate a human skin receptor, potentially helping with skin disorders.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.

Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.

NFIC helps human dental stem cells grow and become tooth-like cells.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.