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Flutamide caused damage to male rat reproductive organs and may affect fertility.

Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

New treatments for male hypogonadism are effective and should be personalized.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Certain fungi and bacteria help orchid seeds germinate and plants grow better.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Men with enlarged prostates often have more severe baldness.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

The document concludes that it's important to understand the placebo effect when evaluating the effectiveness of treatments in medical trials.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Serenoa repens extract in topical products improves hair growth and appearance in male pattern baldness with mild side-effects.

Women with greater androgen sensitivity respond better to finasteride for hair loss.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Some nonsurgical hair loss treatments are effective, especially if started early.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

The conclusion is that treatments like finasteride and minoxidil can prevent baldness progression and improve hair density, but more research is needed on other therapies.

New treatments for PCOS focus on managing symptoms and improving fertility.

Androgenic Alopecia, a common hair loss condition, can be effectively treated with finasteride and other treatments.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Thyroid hormone treatments help thyroidectomized rats grow normally.

Adult stem cells with Tp63 can form hair and skin cells when placed in new skin, showing they have hidden abilities for skin repair.

Bazhengsan reduces inflammation and tissue growth in chronic prostatitis.