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Some patients may experience lasting sexual dysfunction, depression, and other side effects from 5α-reductase inhibitor therapy.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Terazosin and finasteride effectively treat BPH, but combining them adds no extra benefit.

Flutamide and its metabolite can effectively reduce androgen effects.

Men with enlarged prostates often have more severe baldness.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.

Most men with Frontal fibrosing alopecia also lose facial hair and the condition may be linked to hormone levels and sunscreen use.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

Steroid sulfatase inhibitors could potentially treat hormone-related disorders like certain cancers, hair loss, acne, and improve cognitive dysfunction.

5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

Androgenetic alopecia is common, affects self-image, and has no complete cure yet.

Mutations in the AR gene cause hair thinning and loss.

Physalis peruviana extract is more effective in treating benign prostatic hyperplasia in rats than finasteride and terazosine.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

ZD1839, a cancer drug, can cause mild skin rashes that are treatable without stopping the medication.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.

Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.

Finasteride use may increase the risk of male breast cancer.

Large prostates link to more hair loss.

New treatments targeting fibrosis could improve urinary symptoms in BPH.

Chemotherapy for prostate, bladder, and testicular cancer patients commonly causes hair loss, fatigue, and decreased appetite.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Male pattern baldness may predict prostate cancer risk.