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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.

Stinging nettle has compounds that help with joint pain, arthritis, and prostate issues.

TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.

Nano-Pulse Stimulation™ Therapy is more effective and less damaging than cryoablation for treating melanoma tumors in mice.

Anti-androgen therapy might help protect against COVID-19 infection and reduce death risk.

A new gene, JMJD1C, may affect testosterone levels in men.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Finasteride can cause sexual dysfunction, sperm changes, and affect bone density and metabolism.

Testosterone significantly affects urination differences between male and female mice.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.

Most women with too much androgens have PCOS, which can be managed with birth control pills, medication for hair growth, and fertility treatments, and losing weight helps too.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

The document concludes that the immune-inhibitory environment of the hair follicle may prevent melanoma development.

Kidney cancer cells without folliculin are more sensitive to radiation due to increased self-eating cell death.

Saw palmetto extract is generally safe and can effectively treat Lower Urinary Tract Symptoms, but its evaluation is affected by varying quality and a need for long-term studies.

A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.

The man's fatigue and erectile dysfunction were improved by treating his obesity-related low testosterone without needing testosterone replacement.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Finasteride effectively treats baldness but may cause sexual side effects.