research Clinical Applications of Antiandrogens
Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
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research Associations Between Sun Sensitive Pigmentary Genes and Serum Prostate Specific Antigen Levels
Men with less sun-sensitive skin have lower PSA levels, while men with more sun-sensitive skin have higher PSA levels.
research Is Dihydrotestosterone a Classic Hormone?
Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.
research Effect of Finasteride and/or Terazosin on Serum PSA: Results of VA Cooperative Study #359
Finasteride reduces PSA levels, terazosin doesn't affect them, and tracking prostate cancer in patients taking finasteride could be difficult.
research Probing Androgen Receptor Co-Factor Selectivity Profiles: A Chemical Tool to Determine Cross-Talk Between Androgen Receptor and Beta-Catenin In Vivo
PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
research Novel Type 1 5a-Reductase Inhibitors With Antiproliferative Potential On LNCaP Cells
New compounds may help treat prostate cancer by reducing cell growth.
research Triple Hormonal Blockade (ADT3): A Patient’s Perspective
Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
research Intervention in Prostate Cancer: Slight Advantages for Radical Prostatectomy
Men with early balding may have a higher risk of prostate issues, and surgery for prostate cancer has a slight survival benefit over radiation.
research The True Benefit of PSA-Screening: Modeling the Impact of Trial Setting and Protocol on Mortality
PSA screening's effectiveness in reducing prostate cancer deaths can vary based on trial design and participant compliance.
research Androgen Biosynthesis Inhibitors And Androgen Receptor Antagonists
Anti-androgen drugs can treat conditions like prostate cancer and male pattern baldness by blocking effects of testosterone and DHT.
research Potential Adverse Effects of Long-Term Testosterone Therapy
Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.
research Dutasteride
Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
research Regarding Prostate-Specific Antigen: Let's Not Shoot the Messenger
The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.
research A New Way to Restore Tumor Suppressor Function
New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.
research Pharmacology and Potential Use of Cyproterone Acetate
Cyproterone Acetate effectively treats androgen-related conditions and is used in prostate cancer therapy and hormone therapy for transgender women.
research Discovery and Clinical Development of Dutasteride, a Potent Dual 5α-Reductase Inhibitor
Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.
research Patients With a Large Prostate Show a Higher Prevalence of Androgenetic Alopecia
Large prostate links to more hair loss, but age of onset doesn't affect it.
research Pharmacological Basis for Clinical Use of Antiandrogens
Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.
research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)
New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.
research Frontal Fibrosing Alopecia After Antiandrogen Hormonal Therapy in a Male Patient
A male patient developed frontal fibrosing alopecia after antiandrogen therapy for prostate cancer.
research Design, Synthesis and Biological Evaluation of Novel 3-Oxo-4-Oxa-5α-Androst-17β-Amide Derivatives as Dual 5α-Reductase Inhibitors and Androgen Receptor Antagonists
New compounds were made that are promising for prostate cancer therapy.
research In Silico Structural Prediction of Human Steroid 5α-Reductase Type II
Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.
research Finasteride
Finasteride is a medicine used to treat enlarged prostate and prostate cancer, and it works by changing how testosterone works in the body.
research Synthesis and Application of Clinically Approved Small-Molecule Drugs Targeting Androgen Receptor
Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
research 5-Alpha Reductase Inhibitors Use in Prostatic Disease and Beyond
5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.
research Hormone Blocking Anticancer Drugs
The document explains how certain drugs block hormones to treat cancers like breast and prostate cancer.
research Propecia: The Goose That Lays the Golden Eggs
Finasteride is popular for treating male hair loss but may increase the risk of serious prostate cancer and has other potential side effects.
research Pharmacological Basis for Clinical Use of Antiandrogens
Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.
research Tracing the Cellular Origin of Cancer
Understanding where cancer cells come from helps create better prevention and treatment methods.
research Activated Polyamine Catabolism Depletes Acetyl-CoA Pools and Suppresses Prostate Tumor Growth in TRAMP Mice
Overexpressing SSAT enzyme reduces prostate tumor growth in mice.