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The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.

New treatments and diagnostic methods for urological conditions show promise, but some lack sufficient accuracy for clinical use.

New treatments for male hypogonadism are effective and should be personalized.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.

Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

Estrogens and progesterone are key in regulating melasma pigmentation.

A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

People with early-onset hair loss (AGA) have a higher risk of heart disease, metabolic syndrome, and prostate enlargement.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Lespedeza cuneata extract may help treat enlarged prostate.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

Finasteride, a hair loss medication, may be linked to stroke in young men.

Tamsulosin may slightly increase dementia risk compared to other treatments for enlarged prostate.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

Finasteride treatment for three years changes certain polyamine levels in the blood but not in urine.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

Men with low testosterone should be carefully evaluated and monitored before and during treatment.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Omega-6 fats in certain cells boost male hormone production.

Quercetin may help improve symptoms of polycystic ovary syndrome.

Eating apples can help prevent heart disease, cancer, and other conditions because they have healthy plant chemicals.