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5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.

Finasteride can cause one-sided breast enlargement, which disappears after stopping the drug.

Finasteride doesn't affect bone density in male rats.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

The normal human prostate does not significantly affect blood DHT levels.

Future osteoporosis treatments should focus on increasing bone growth, with many promising options available.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Testosterone therapy can help improve mood, sexual function, and bone health in women with low androgen levels, but more research is needed to establish safe and effective guidelines.

Patients with myotonic dystrophy often have skin problems that suggest early aging and vitamin D issues, and the severity of these problems is linked to their genetic condition and vitamin D levels.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

A patient with Satoyoshi syndrome improved with a treatment combining several medications, including carbamazepine and methotrexate.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.