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The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Testosterone therapy increases bone density in older men with low testosterone levels.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Oestrogens are key for bone growth during puberty in both boys and girls.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.