7 citations,
July 2011 in “Survey of Ophthalmology” The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.
June 2019 in “International journal of dermatology and venereology” The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.
1 citations,
November 2016 in “International Journal of Research in Dermatology” The study found no significant link between the symptoms, tissue analysis, and immunofluorescence results in scarring hair loss conditions.
18 citations,
October 2012 in “Dermatologic Clinics” Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.
5 citations,
December 2005 in “Clinical Techniques in Equine Practice” Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.
New insights into cell communication in psoriasis suggest innovative drug treatments.
49 citations,
September 2007 in “Journal of Investigative Dermatology” The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
29 citations,
January 2016 in “Annals of dermatology/Annals of Dermatology” Arachidonic acid helps hair grow by increasing growth factors and improving follicle health.
86 citations,
October 2017 in “Clinics in Dermatology” Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.
32 citations,
January 2006 in “Acta dermato-venereologica” SACUMAN, a rare condition causing hair loss without clear signs, is often misdiagnosed and needs scalp biopsies for accurate detection.
32 citations,
March 2014 in “PLOS ONE” Mice lacking fibromodulin have disrupted healing patterns, leading to abnormal skin repair and scarring.
57 citations,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
50 citations,
January 2016 in “The FEBS journal” RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.
3 citations,
July 2015 in “European Journal of Dermatology” AGEs may cause hair loss by increasing inflammation in hair follicles.
12 citations,
February 2010 in “Journal of The American Academy of Dermatology” A cancer drug caused unusual hair growth on a 100-year-old man's scalp and eyelashes.
July 2023 in “Journal of Clinical Medicine” The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
16 citations,
February 2019 in “Journal of Cellular and Molecular Medicine” Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
14 citations,
September 2016 in “Journal of Cutaneous Pathology” The document concludes that new methods improve the accuracy of diagnosing scalp alopecia and challenges the old way of classifying it.
9 citations,
January 2005 in “Pediatric Dermatology” Fox Fordyce disease can occur in prepubertal girls and may be underdiagnosed.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
52 citations,
October 2012 in “Journal of Dermatological Science” The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
256 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
38 citations,
January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
141 citations,
August 2018 in “Nature Reviews Microbiology” Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
23 citations,
April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
May 2017 in “InTech eBooks” Some hair loss disorders cause permanent loss due to scarring, and treatments like steroids don't always work well.
January 2005 in “Pediatric Dermatology” Alopecia areata in infants may be more common than previously thought.
49 citations,
August 2004 in “The FASEB Journal” Mice with human skin protein K8 had more skin problems and cancer.
94 citations,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.