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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The editor suggests removing "race" and "ethnicity" from dermatology and creating tools to objectively assess skin color and hair texture.

Low serum ferritin levels are not closely linked to telogen effluvium in women.

Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.

Hair loss in postmenopausal women due to ovarian hyperthecosis is rare, but removing the ovaries can significantly improve the condition.

About 40% of women by age 60 experience significant hair loss, often due to androgenetic alopecia, with treatments like minoxidil available and hope for future cures.

Sudden weight loss can cause significant hair loss, and using colchicine on the skin for psoriasis may be unsafe.

PCOS affects many women and requires early detection and symptom management.

Trichotillomania can cause severe complications like hairballs in the stomach, needing surgery and psychiatric care.

Most women with depression in the study had low vitamin D levels.

Pregnant women with Systemic Lupus Erythematosus have a higher risk of blood clotting problems.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Melatonin protects skin and hair from damage and stress by acting as an antioxidant and influencing cell growth.

Different hair diseases affect people during childbearing years, with treatments ranging from medication to psychological support.

Herbal remedies can cause adverse effects and need more safety research.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Finasteride effectively treats hidradenitis suppurativa for most patients.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Chronic Telogen Effluvium is a hair loss condition in middle-aged women that usually doesn't lead to complete baldness.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.