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Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

RANK-RANKL signaling is essential for hair growth and skin health.

EdnrB signaling helps melanocyte stem cells regenerate and could be targeted to treat pigmentation issues.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

The study suggests smoking is common in HS patients but its role is unclear, and more research is needed to understand HS causes.

HIV can cause unusual and severe skin problems that are hard to treat.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Male pattern baldness involves three mechanisms and finasteride can help reverse it.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.

Chemokine signaling is important for hair development.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

A mother's western diet can make her milk toxic, causing inflammation and hair loss in babies.

The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.