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Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Nanotechnology shows promise for better chronic wound healing but needs more research.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Advanced human skin models improve drug development and could replace animal testing.

Many treatments for hair loss show potential, but more testing is needed to confirm their effectiveness. Only minoxidil for women and minoxidil and finasteride for men are FDA approved.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.

Dutasteride is more efficient than finasteride, but individual results vary.

Finasteride reverses early hair loss and promotes growth.

The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.

Topical glucocorticoids thin the skin and change collagen structure.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Robotic hair transplantation with AI offers more reliable, precise, and efficient hair restoration.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.

Stem cell therapy helps heal burn wounds, especially second-degree burns, by promoting blood vessel growth and reducing inflammation.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

The Scalp Coverage Scoring method reliably measures hair density from images.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Raspberry ketone lacks sufficient human research to support health benefit claims and requires more rigorous studies to confirm its safety and effectiveness.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.