research Is There an Association Between 5α-Reductase Inhibitors and Metabolic Syndrome? A Narrative Review of the Literature
Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.
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90-120 / 1000+ results research Safety, Tolerability, and Pharmacokinetics of Topical Calcitriol Formulation for Treatment of Chemotherapy-Induced Alopecia in Patients Receiving Taxane-Based Regimen: Final Results
Topical calcitriol was safe and well-tolerated for potential hair loss prevention in chemotherapy patients.
research The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19
Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.
research Advancements in Regenerative Medicine for Aesthetic Dermatology: A Comprehensive Review and Future Trends
New regenerative techniques show promise for improving skin, healing wounds, and growing hair.
research The Immunology of the Porcine Skin and Its Value as a Model for Human Skin
Porcine skin is very similar to human skin, making it a useful model for research.
research Current Stem Cell Technologies Used in Medicine
Stem cell technologies are mostly effective in treating diseases and repairing tissues.
research Treatment Advances for Acne Vulgaris: The Scientific Role of Cannabinoids
Cannabidiol shows promise as an effective treatment for acne.
research Advances in Stem Cell-Based Therapy for Hair Loss
Stem cell therapies show promise for treating hair loss, but more research is needed to understand their safety and effectiveness.
research MicroRNAs in the Skin: Role in Development, Homeostasis, and Regeneration
MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
research Review of the Effects of 17α-Estradiol in Humans: A Less Feminizing Estrogen with Neuroprotective Potential
17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
research Unlocking the Potential of the Secretome in Hair Growth Enhancement
Secretome-based therapies could improve hair growth better than current treatments.
research Potassium Channel Openers: Pharmacological and Clinical Aspects
Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.
research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research The Effect of Finasteride, a 5 Alpha-Reductase Inhibitor, on Scalp Skin Testosterone and Dihydrotestosterone Concentrations in Patients with Male Pattern Baldness
Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
research Promotion of Anagen, Increased Hair Density, and Reduction of Hair Fall in a Clinical Setting Following Identification of FGF5-Inhibiting Compounds via a Novel 2-Stage Process
New compounds were found to help increase hair growth and decrease hair loss.
research Development of Modified Montmorillonite-Bacterial Cellulose Nanocomposites as a Novel Substitute for Burn Skin and Tissue Regeneration
New nanocomposites with copper show promise for healing burn wounds and regenerating skin.
research Clinical Picture, Diagnosis, Treatment, and Outcome of Severe Acute Respiratory Syndrome (SARS) in Children
Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.
research Photobiomodulation: The Clinical Applications of Low-Level Light Therapy
Low-Level Light Therapy (LLLT) is a safe and effective method for skin rejuvenation, acne treatment, wound healing, body contouring, and hair growth, but more well-designed trials are needed for confirmation.
research Clinical Applications of Antiandrogens
Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
research Trends in the Development of New Drugs for the Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
research Analysis of Animal Models of Alopecia Areata Based on Clinical Features of Traditional Chinese and Western Medicine
Better models and evaluation methods for alopecia areata are needed.
research Pharmacological Activity and Clinical Use of Polydeoxyribonucleotide
PDRN helps repair tissue and improve wound healing with a high safety profile.
research MmuPV1 Infection and Tumor Development in T Cell-Deficient Mice Prevented by Passively Transferred Hyperimmune Sera from Normal Congenic Mice Immunized with MmuPV1 Virus-Like Particles
Giving immune serum from vaccinated mice to mice without T cells prevents infection and tumor growth.
research Development and Validation of Androgen-Induced Hair Loss and Anagen Induction Mouse Models for Pharmacological Evaluation of Anti-Androgenic Agents
The mouse models are effective for testing new hair loss treatments.
research Topically Used Herbal Products for the Treatment of Hair Loss: Preclinical and Clinical Studies
Herbal products might promote hair growth with fewer side effects, but more research is needed to confirm their safety and effectiveness.
research Combined Therapy with Adipose Tissue-Derived Mesenchymal Stromal Cells and Meglumine Antimoniate Controls Lesion Development and Parasite Load in Murine Cutaneous Leishmaniasis Caused by Leishmania Amazonensis
Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.
research A Segmental Approach to Scoring Hair Density from Global Images: Introducing the Scalp Coverage Scoring Method for Clinical Trials and Practice
The Scalp Coverage Scoring method reliably measures hair density from images.
research Brown Adipose Tissue as an Innovative Approach for Polycystic Ovary Syndrome Treatment: A Narrative Review
More research is needed before using brown fat to treat polycystic ovary syndrome.
research Bioengineering Skin Using Mechanisms of Regeneration and Repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.