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Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Testosterone is crucial for development, growth, and various body functions in mammals.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Aquaporins could be new drug targets for treating polycystic ovary syndrome.

Specific genes influence hair and cashmere growth in Laiwu black goats.

Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

PCOS increases the risk of heart disease and type 2 diabetes in women.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.

EDA signaling is linked to skin disorders, various cancers, and liver disease.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.