41 citations
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June 2023 in “Antioxidants” This review highlights that pomegranate exhibits promising beneficial effects in preclinical and clinical studies for cardiovascular and non-cardiovascular diseases, though further research is needed on its bioavailability and metabolites for effective therapeutic use.
14 citations
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April 2021 in “Heliyon” This study found that both alcoholic and aqueous extracts of Punica granatum L. showed potential for promoting hair growth and exhibited anti-lice and antidandruff activities in a mouse model.
2 citations
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January 2025 in “Veterinary Dermatology” This study found that Pomeranian dogs with a woolly coat type and male dogs had a higher risk of developing Alopecia X in the Netherlands and Belgian regions studied.
1 citations
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January 2020 In this study, researchers formulated a herbal shampoo using natural ingredients like Pomegranate, Curry Leaves, and Ginger, and reported good cleansing properties, froth stability, and conditioning performance, though they suggest further scientific validation to confirm overall quality.
1 citations
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September 2019 in “Pomeranian Journal of Life Sciences” This study found that Demodex infestation was present in 21% of healthy volunteers, with higher rates in older individuals and more common in PUM personnel than students.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a polyherbal shampoo with pomegranate peel and activated charcoal, finding it offered good cleansing ability, stable foam, and scalp-friendly pH without causing irritation, suggesting it may be a safe and effective alternative to synthetic shampoos for pollution-related hair protection.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated a polyherbal shampoo enriched with pomegranate peel extract, reporting good cleansing ability, stable foam, scalp-friendly pH, and no irritation, suggesting it could be a safe, effective alternative for protecting hair from pollution-related damage.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated polyherbal formulations for managing hair issues such as dandruff, dryness, premature greying, baldness, and hair fall, but it reports no new clinical results.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study assesses the effectiveness of polyherbal formulations in managing hair issues such as dandruff, dryness, premature greying, baldness, and excessive hair fall, in response to increasing hair loss among younger individuals due to stress, poor diet, and chemical use.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that formulation F6 of the tested creams had superior stability and antioxidant potential, making it the most effective among the formulations.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In laboratory tests, this study evaluated several skin cream formulations and reported that formulation F6 showed superior stability and strong antioxidant potential, while all formulations were stable, of uniform consistency, had a suitable pH, and were non-irritant to the skin.
November 2025 in “Communications Materials” This research demonstrated that transforming pomelo peel into expanded sponges and carbonized aerogels can accelerate hemostasis and enhance healing in diabetic wounds while eradicating bacterial biofilms, offering an eco-friendly solution for wound care from agricultural waste.
March 2025 in “Dental Journal (Majalah Kedokteran Gigi)” This study developed a biodegradable gelatin and chitosan hemostatic sponge, enhanced with pomegranate peel extract, for dental applications, highlighting its effective antibacterial properties, improved blood absorption, and reduced clotting time, suggesting potential for use in clinical dental and wound care procedures.
February 2024 in “International Journal of Scientific Research in Science and Technology” This literature review outlines the traditional uses, nutritional composition, and bioactive compounds of pomegranate plants, highlighting their varied pharmacological actions such as antibacterial, antiviral, anticancer, and antioxidant effects, and discusses the peel's chemical composition and toxicology.
September 2023 in “Repository of the University of Primorsk (University of Primorska)” This review discusses the side effects of gender-affirming hormone therapy and reports no clinical results; it highlights the potential to reduce adverse effect risk factors with healthy eating guidelines.
April 2023 in “International Journal of Science and Research (IJSR)” This study focuses on developing a natural herbal shampoo using pomegranate peels and other plant-based ingredients to enhance hair growth, strength, and darkening while maintaining safety and efficacy compared to chemical-based alternatives.
October 2020 in “Journal of bio innovation” In this study, DanEra, an herbal hair tonic from Pomegranate and Beetroot extracts, showed equivalent effectiveness to the standard drug Ketoconazole in microbiological tests and provided significant relief from severe dandruff in all volunteers within 10 days.
October 2020 in “Misr journal of agricultural engineering” This study examined the drying of pomegranate peel as a method for reducing waste and found that drying efficiency varied with temperature and air velocity, potentially adding value to this by-product.
April 2024 in “JURNAL ILMU KEFARMASIAN INDONESIA” This study examined how varying concentrations of kaolin base in mud masks with red pomegranate peel extract influenced properties like viscosity, pH, and drying time, finding that a formulation with 22.5% kaolin performed best in terms of physical characteristics and enzyme inhibition.
20 citations
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July 2006 in “Veterinary dermatology” This study found that hair regrowth in Pomeranians with hair cycle arrest treated with melatonin was not associated with a change in oestrogen receptor-α staining.
14 citations
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June 2024 in “Food Chemistry X” This review highlights that pomegranate leaf exhibits potential health benefits, such as anti-cancer, anti-diabetic, anti-inflammatory, and neuroprotective effects in vitro and in animal models, but calls for comprehensive human clinical trials to confirm these therapeutic benefits and ensure safety.
2 citations
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January 2005 in “The Japanese Journal of Veterinary Dermatology” In this study, Pomeranians with non-illness, generalized alopecia did not exhibit adrenal or pituitary abnormalities, suggesting a breed-specific hormonal pattern as a potential cause rather than a functional adrenal anomaly.
April 2026 in “Veterinary Record Case Reports” In this case study, a 2-year-old Pomeranian dog from Mizoram, India, with alopecia X showed significant hair growth and improved skin condition after undergoing neutering and receiving omega-3 and omega-6 fatty acid supplements.
February 2026 in “Veterinary Dermatology” This study found that Pomeranians with Alopecia X had fewer follicles per group, more fragile hair, and distinct hair cycle stages compared to non-alopecic Pomeranians, highlighting coat-type differences significant for diagnosing the condition.
February 2025 in “Buletin Veteriner Udayana” In this case report, a 6-year-old Pomeranian crossbreed with scabies showed improvement after treatment with ivermectin, chlorpheniramine maleate, fish oil, vitamins, and specialized shampoo over 16 days, with reduced pruritus and hair regrowth.
January 2025 in “Brazilian Journal of Veterinary Medicine/Revista Brasileira de Medicina Veterinária” This source describes the first successful use of a deslorelin acetate implant to treat alopecia X in a neutered female dog, achieving profuse hair regrowth in 9 months, suggesting an uncomplicated and cost-effective alternative after melatonin failure.
January 2024 in “International Journal of Veterinary Sciences and Animal Husbandry” This case report described a 4-year-old Pomeranian dog diagnosed with Demodex canis infestation, which showed complete recovery from skin lesions and other symptoms after a 35-day treatment regimen that included ivermectin injections, amitraz baths, and oral antibiotics.
18 citations
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February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.
1 citations
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September 2024 in “Veterinary Dermatology” In this study, clinicians are advised to perform trichography regularly on Pomeranians with HCA, as significant hair abnormalities, especially TN, may affect hair quality; further research is needed to understand the underlying mechanisms and treatment options.
1 citations
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January 2024 in “Veterinary Dermatology” In this study, researchers cloned a two-year-old Pomeranian with Alopecia X after its accidental death and found that the cloned dog developed the same hair lesions at the same age, suggesting the condition is genetically driven rather than environmentally influenced.