47 citations
,
June 2015 in “Medicines” This review examines the use and efficacy of Panax ginseng in various clinical settings, noting that clinical trial outcomes vary widely based on study conditions and ginseng types; no new results are reported.
46 citations
,
August 2019 in “Journal of Ethnopharmacology” This review compiles current information about Eclipta prostrata, traditional uses, and its promising pharmacological properties, like hepatoprotective and anti-inflammatory effects, but emphasizes that more research is needed to fully understand its mechanisms and ensure safety for clinical application.
45 citations
,
December 1991 in “Annals of the New York Academy of Sciences” This article discusses the distribution of extracellular matrix molecules in human hair follicles and reports no new results.
45 citations
,
February 2018 in “Journal of basic and clinical physiology and pharmacology/Journal of basic & clinical physiology & pharmacology” This review summarizes the ethno-medicinal uses, phytochemical constituents, and biological activities of Acorus calamus, highlighting its potential therapeutic benefits and the importance of further scientific work on this plant.
44 citations
,
August 2012 in “Journal of Food Science” This study optimized conditions for extracting saponins from Eclipta prostrata, achieving maximum yield with specific ethanol concentration, time, temperature, and liquid/solid ratio.
43 citations
,
February 2020 in “Clinica chimica acta” This review discusses the role of phytochemical nanoparticles in cervical cancer therapy and reports no new clinical results; the authors highlight their potential advantages over conventional chemotherapy.
43 citations
,
July 2019 in “Stem Cells International” This review discusses advances and challenges in skin tissue engineering, focusing on developing 3D constructs for functional skin substitutes, and reports no new clinical results.
43 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews innovations in hair cosmetics, focusing on esthetic procedures and products in the Indian market, and reports no new experimental findings.
42 citations
,
January 2021 in “Journal of Clinical Medicine” This review discusses advancements in the use of microneedle arrays and nanoparticles for transdermal delivery of therapeutics, noting challenges in overcoming the skin barrier and summarizing recent clinical trial achievements in areas like cancer therapy and gene therapy.
42 citations
,
September 2017 in “Advances in protein chemistry and structural biology” This chapter reviews surface plasmon resonance (SPR) methodology and its applications in basic science and human disease without reporting new clinical results.
42 citations
,
January 2024 in “Frontiers in Endocrinology” This review discusses polycystic ovary syndrome treatments, focusing on the potential benefits and safety of herbs and phytochemicals, and reports no new clinical results.
42 citations
,
March 2014 in “European Journal of Pharmacology” This study found that minor ginseng saponin F2 may promote hair growth more effectively than finasteride by enhancing anagen induction and modulating the Wnt signaling pathway in cell and mouse models.
41 citations
,
July 2020 in “Colloids and surfaces. B, Biointerfaces” This study suggests that adjusting the ratios of keratin-associated proteins to keratin intermediate filaments can create keratin/chitosan hydrogels with more consistent gel properties for tissue engineering.
41 citations
,
September 2017 in “Advanced Healthcare Materials” This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.
41 citations
,
July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
40 citations
,
August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
40 citations
,
June 2013 in “Molecular Pharmaceutics” This study demonstrates that transfected epidermal stem cells using a novel 3D transfection system significantly enhanced wound healing and may serve as an effective therapeutic agent and gene delivery method for wound treatment.
39 citations
,
June 2017 in “Journal of Applied Research on Medicinal and Aromatic Plants” This review examines around 68 plant sources from six major plant families, assessing their scientific rationale and use by the cosmeceutical industry for applications like anti-ageing and sun protection.
38 citations
,
June 2018 in “Plant & cell physiology/Plant and cell physiology” This study found that overexpressing PLC5 in Arabidopsis thaliana reduced root growth but improved drought tolerance, and suggests PIP2 is crucial for root hair growth.
37 citations
,
December 2024 in “Theranostics” In this study, a newly developed nanoparticle-loaded hydrogel wound dressing demonstrated significant antibacterial, antioxidant, anti-inflammatory, and proangiogenic activities, effectively reducing pain and promoting healing in a murine burn wound model while preventing infection by *Staphylococcus aureus*.
37 citations
,
January 2019 in “Food science & nutrition” This review summarizes various effects of bergamot components on multiple health conditions in humans and animals but reports limitations in their use for stress and anxiety relief in aromatherapy.
37 citations
,
August 2014 in “Journal of experimental botany” This study identified the AtPRPL1 gene in Arabidopsis thaliana as being involved in cell elongation processes, despite unclear changes in cell wall composition from its altered expression.
36 citations
,
June 2019 in “eLife” This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.
36 citations
,
January 2014 in “Elsevier eBooks” This narrative review discusses the structure and functions of the skin, focusing on its barrier role, self-repair, thermoregulation, and immune functions, and reports no new experimental results.
36 citations
,
August 2011 in “Journal of Controlled Release” This review explores the potential of using genetically-manipulated stem cells as both therapeutic agents and gene delivery vehicles for enhanced wound regeneration, but it reports no new clinical results.
35 citations
,
February 2006 in “Textile Research Journal” This study found that xylanase and pectinase enzymes clean wool and specialty hair fibers as effectively as soap, without causing physical damage, whereas resinase was not effective.
33 citations
,
May 2019 in “Aesthetic Plastic Surgery” This review found that most studies support the effectiveness and safety of using hyaluronic acid fillers and laser treatments together for facial rejuvenation, but highlights that the evidence is limited to small, nonrandomized studies and additional research is necessary.
33 citations
,
April 2011 in “Journal of Veterinary Internal Medicine” This study found that inhaled fluticasone for 11 months did not adversely affect the immune function or response to vaccination in horses with heaves.
32 citations
,
December 2014 in “Journal of experimental botany” In this study, the authors concluded that arabinogalactan proteins recognized by specific antibodies are involved in the differentiation and development of barley root epidermal cells, contributing to root hair development.
32 citations
,
January 2021 in “Molecules” This review compiles studies on the antidiabetic potential of plants from the Middle East, particularly from the Asteraceae and Lamiaceae families, but reports no clinical results.