72 citations
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June 2019 in “International Journal of Cosmetic Science” This review discusses the biological properties of 18β‐glycyrrhetinic acid derived from licorice root, highlighting its potential anti-inflammatory, antioxidant, and antimicrobial benefits in treating dermatological disorders, and reports no new experimental results.
November 2025 in “Pharmacological Research” In this study, researchers found that exosome-like nanoparticles isolated from Polygoni Multiflori Radix can promote hair growth in mice by modulating androgen signaling and gene expression, outperforming Minoxidil in testosterone-induced conditions.
December 2024 in “Frontiers in Pharmacology” In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.
7 citations
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February 2013 in “Tropical Journal of Pharmaceutical Research” In this study, applying G. glabra root extract to female rats resulted in faster and more extensive hair growth than minoxidil or a control treatment.
5 citations
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September 2024 in “Biomolecules and Biomedicine” This study found that total glucosides of paeony (TGP) reduced hair loss and inflammation in alopecia areata mice by inhibiting cellular pyroptosis.
March 2024 in “Nutrients” This study found that Gynostemma pentaphyllum leaf hydrodistillate (GPHD) promoted hair growth in mice similarly to minoxidil and upregulated growth factor expression via the AKT/β-catenin signaling pathway, with damulin B identified as an active component contributing to these effects.
38 citations
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January 2002 in “Biological & Pharmaceutical Bulletin” This study reported that the aqueous ethanol extract of Lygodii Spora demonstrated in vitro testosterone 5alpha-reductase inhibition and in vivo anti-androgenic activity, potentially due to oleic, linoleic, and palmitic acids.
September 2025 in “Discover Chemistry.” This review explores the phytopharmacological and nutritional benefits of Alpinia rhizomes, commonly used in Southeast Asian traditional medicine, highlighting their potential antioxidant, antimicrobial, and anti-inflammatory properties while emphasizing the need for further research to validate these uses and consider their nutraceutical and pharmaceutical applications.
March 2026 in “Food Science & Nutrition” In this study, high-dose Arachis hypogaea root extract significantly reduced prostate weight and markers of glandular hyperplasia in testosterone-induced BPH in mice, with associated changes in inflammatory gene expression and beneficial shifts in gut microbiota.
4 citations
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October 2013 in “Botanics Targets and Therapy” In this animal study, a herbal preparation demonstrated moderate anti-inflammatory and immunomodulating properties, suggesting its potential usefulness for preventing and treating alopecia.
October 2025 in “Interdiciplinary Journal and Hummanity (INJURITY)” This study characterized bioactive compounds in extracts from six Kalimantan herbal plants, confirming traditional medicinal uses with findings such as triterpenoids and several potent compounds with antimicrobial and cardiovascular benefits, laying groundwork for potential therapeutic applications and conservation efforts.
January 2018 in “The Korea Journal of Herbology” This study found that water extract of Puerariae Radix may promote hair growth by increasing the mRNA expression levels of hair growth-related genes in human dermal papilla cells, unlike the juice extract.
3 citations
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December 2019 in “International Journal of Pharmacology” This study found that Poria cocos extract may enhance human follicle dermal papilla cell proliferation through the AKT signaling pathway, indicating its potential for hair growth promotion.
April 2025 in “Antioxidants” In this study, the researchers found that the water-soluble fraction of Rhus semialata gall extract and its component Penta-O-Galloyl-β-D-Glucose promoted hair growth in human dermal papilla cells, and clinical trials supported these findings, showing improved hair density and appearance compared to placebo.
July 2026 in “International Journal of Molecular Sciences” This study found that TSG-enriched Polygonum multiflorum extract, optimized through microwave-assisted and chromatographic methods, promotes hair regrowth in a mouse model of androgenetic alopecia via 5α-reductase inhibition and Wnt/β-catenin pathway activation, suggesting its potential as a natural treatment.
17 citations
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April 2015 in “Tropical Journal of Pharmaceutical Research” This review highlights the traditional use and potential therapeutic activities of Asiasari Radix in drug discovery, but it reports no new clinical results.
2 citations
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February 2012 in “PubMed” This study found that Gp₄G increased hair length, papilla cell numbers, and versican deposition in treated animals, potentially through alterations in hair follicle phases and nucleotide concentrations.
April 2026 in “Inflammopharmacology” This study found that Punica granatum ethanolic leaf extract may alleviate skin fibrosis in rats by modulating inflammation-related pathways and reducing dermal alterations.
In this study, the ethanol extract of Tridax procumbens leaves exhibited antimicrobial activity against both Gram-positive and Gram-negative bacteria, with specific active compounds identified through GC-MS analysis that may contribute to its therapeutic potential.
11 citations
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October 2021 in “Carbohydrate Polymers” In this study, WGBP-A2 polysaccharides from Ginkgo biloba leaves promoted hair growth and altered inflammation markers in alopecia areata mice, suggesting potential therapeutic effects through modulation of inflammation pathways.
October 2017 in “Institutional Repositories DataBase (IRDB)” Polyacetylene compounds from Panax ginseng may slow hair growth.
This study concluded that the antioxidant and hair growth activity of Trigonella plants were higher compared to Geranium wallichianum, with a potential correlation between antioxidant activity and hair growth in albino rats.
32 citations
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December 2014 in “Journal of experimental botany” In this study, the authors concluded that arabinogalactan proteins recognized by specific antibodies are involved in the differentiation and development of barley root epidermal cells, contributing to root hair development.
March 2026 in “Current Bioactive Compounds” In a rat model, this study observed that applying high-concentration (100%) P. europaea root extract topically significantly enhanced hair growth by increasing the number of hair follicles, hair shaft diameter, and hair length compared to controls, suggesting its potential as a treatment for alopecia.
June 2022 in “Pham Ngoc Thach Journal of Medicine and Pharmacy” This study identified key natural compounds such as polyphenols and flavonoids in tongue fern and established optimal extraction conditions using methanol.
58 citations
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December 2021 in “Phytomedicine Plus” This review article compiles past and updated information on Tridax procumbens' traditional uses and chemical compounds, highlighting its diverse pharmacological activities such as wound healing, but emphasizes the need for further toxicological research.
11 citations
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November 2015 in “Journal of Functional Foods” This study found that the ethyl acetate fraction of Hibiscus rosa sinensis petals significantly reduced serum glucose and glycated hemoglobin levels in diabetic rats, with effects comparable to metformin.
4 citations
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August 2023 in “Journal of Cosmetic Dermatology” Gynostemma pentaphyllum extract may help grow hair and prevent graying.
1 citations
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June 2023 in “Pharmacognosy Research” This review highlights the promising therapeutic potential of Bacopa monnieri in treating various health conditions, particularly related to neuropharmacology, but emphasizes the need for further clinical research.
May 2023 in “Journal of pharmacognosy and phytochemistry” This study conducted a comprehensive pharmacognostic and phytochemical analysis of Sphagneticola calendulacea stem, identifying tannin-filled cells, various secondary metabolites, and significant physicochemical characteristics, which could aid in authenticating the plant for therapeutic use.