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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Fatty acid transport protein 4 is essential for skin and hair development.

Lower SHBG levels may increase the risk of PCOS.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

TRH stimulates human hair growth and extends the hair growth phase.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Testosterone may slow down wound healing and increase inflammation.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.