January 2026 in “International Journal for Research in Applied Science and Engineering Technology” This source reviews PCOS, emphasizing its complex etiology involving genetic and metabolic factors and highlighting reproductive and long-term health risks. It notes evolving diagnostic criteria and stresses the importance of early diagnosis and personalized management to improve outcomes.
1 citations
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July 2025 in “BMC Medicine” The authors concluded that establishing and standardizing methods for data collection are crucial to improving PCOS diagnosis and research due to challenges observed in data harmonization across diverse international cohorts.
6 citations
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May 2017 in “Nursing standard” This article discusses the pathophysiology, diagnosis, and treatment of polycystic ovary syndrome and explores its complications and psychosocial effects, but reports no new clinical findings.
28 citations
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February 2012 in “PLoS ONE” In this study, researchers identified a novel congenital skin disorder in Chesapeake Bay retrievers, linked to a plakophilin-1 deficiency due to a genetic mutation, marking the first known occurrence in an animal species.
15 citations
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February 2015 in “Cell & tissue research/Cell and tissue research” This review examines the role of P-cadherin in skin and hair biology, emphasizing its importance in human hair growth, cycling, and pigmentation, and reports no new research findings.
July 2019 in “International Journal of Advance Research in Community Health Nursing” This study observed that, among women in Padgampora Village, J&K, aged 15-45, 42.5% had PCOS between ages 15 and 25, with clinical signs like irregular cycles, obesity, acne, and more, highlighting the need for increased awareness and early intervention.
March 1998 in “Journal of dermatological science” Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.
In this study of women in Swabi, 26.04% were diagnosed with Polycystic Ovary Syndrome, with Hyperandrogenism and phenotype A being the most common presentations.
5 citations
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October 2021 in “Meditsinskiy sovet = Medical Council” This review discusses diagnostic criteria, phenotypes, and therapies for polycystic ovarian syndrome, emphasizing an individualized treatment approach based on the multifactorial nature of the disease; it reports no clinical results.
March 2026 in “International Journal of Science Strategic Management and Technology” This research introduces WomenCare, a web-based system using a machine learning model to predict PCOD risk by evaluating factors like age, BMI, and lifestyle habits; it aims to help women monitor their health but is not a substitute for a professional diagnosis.
81 citations
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February 2019 in “Experimental & Molecular Medicine” This review examines PAK4 signaling pathways in prostate cancer, Parkinson's disease, and melanogenesis, focusing on the potential role of the PAK4-CREB axis, without reporting new clinical results.
November 2025 in “IntechOpen eBooks” This chapter reviews the complex relationship between PCOS and sexual dysfunction, highlighting its fundamental role as a biopsychosocial manifestation rather than a secondary complication, and calls for comprehensive, patient-centered care; it reports no new clinical results.
63 citations
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January 1999 in “The Journal of Clinical Endocrinology & Metabolism” This study found evidence suggesting a potential genetic link between polycystic ovaries and premature male pattern baldness through screening of first-degree relatives of women with polycystic ovary syndrome.
74 citations
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September 2003 in “The Journal of Immunology” This study found that PKCα activation in transgenic mice induces keratinocyte apoptosis and mediates neutrophilic skin inflammation via different pathways, suggesting potential mechanisms for cutaneous inflammatory diseases.
April 2023 in “Elsevier eBooks” This review discusses the various phenotypes and systemic manifestations of polycystic ovary syndrome, including metabolic, reproductive, and psychological aspects, but reports no new clinical results.
24 citations
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June 2015 in “Journal of Investigative Dermatology” This study observed that epidermal-specific deletion of aPKCλ in mice disrupts hair follicle stem cell quiescence, leading to altered hair follicle cycling and skin anomalies.
10 citations
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December 2015 in “International Journal of Molecular Sciences” This study suggests that PDCD4 regulates keratinocyte proliferation and contact inhibition, playing a role in epidermal homeostasis and wound healing.
2 citations
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January 2016 in “Knowledge Commons (Lakehead University)” This study investigates the experiences of women with PCOS to increase understanding, reduce stigma, and enhance education about the syndrome for all women.
April 2026 in “Clinical Dermatology Review” In this study, patients with keratosis pilaris exhibited significant quality of life impairment, with histopathology and dermoscopy revealing consistent skin and hair changes.
5 citations
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October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a high-risk allele in the PLCD1 gene associated with hereditary trichilemmal cyst formation, proposing a monoallelic two-hit mechanism as the underlying genetic pathogenesis.
1 citations
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March 2023 in “Tidsskrift for Den norske lægeforening” This article provides an overview of keratosis pilaris, discussing its different variants, possible pathogenesis, and treatment options, without reporting new clinical results.
135 citations
,
October 1999 in “Journal of Cell Science” This study found that overexpression of PKCα in mouse epidermis increases expression of specific proinflammatory mediators and induces inflammation but does not significantly affect epidermal differentiation, proliferation, or tumor promotion with TPA.
July 2023 in “Journal of Controversies in Obstetrics & Gynecology and Pediatrics” This review provides an overview of polycystic ovary syndrome, including its causes, symptoms, diagnosis, and treatment strategies, and reports no new research findings.
October 2024 in “Journal of the American Society of Nephrology” This study found that in a large cohort of chronic kidney disease patients, nonprogression or regression of the disease was more common than progression or kidney failure, especially with advancing age.
September 2015 in “University of Southern Denmark Research Portal (University of Southern Denmark)” This guideline provides a concise evidence-based overview of various aspects of polycystic ovary syndrome, including diagnosis and follow-up of secondary effects, but reports no new clinical results.
1 citations
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November 2023 This study examined the prevalence and management of PCOD, finding that it primarily affects unmarried women aged 18-25, causing symptoms like irregular periods and infertility, with many opting for medication and lifestyle changes despite mixed beliefs about their effectiveness.
11 citations
,
August 2018 in “Endokrynologia Polska” This consensus paper reviews current challenges and recommendations for diagnosing and treating polycystic ovary syndrome, highlighting the utility of the Rotterdam criteria for adults and different criteria for teenagers without requiring polycystic ovaries.
3 citations
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March 2018 in “Journal of Continuing Education in Nursing” This study found that a continuing education program significantly improved rural nurse practitioners' knowledge about assessing, diagnosing, and managing PCOS.
July 2023 in “International journal of yogic, human movement and sports sciences” This study comprehensively analyzes a specific disease, detailing its prevalence, diagnostic criteria, and various types and subtypes, aiming to enhance understanding and guide personalized management strategies for improved patient outcomes.
4 citations
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January 2025 in “Clinical Cosmetic and Investigational Dermatology” This article reviews the characteristics, differential diagnosis, and management options for papular acantholytic dyskeratosis of the vulva, illustrated by a case of a 21-year-old patient, but reports no new clinical results.