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AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Telogen effluvium is a reversible hair loss condition that requires a detailed diagnosis and often resolves on its own.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Noggin is necessary to start the hair growth phase in skin after birth.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Sebocytes play a key role in controlling androgen levels in human skin.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Estrogen therapy can reduce skin aging but has cancer risks.

Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Cathepsin L is essential for normal hair growth and development.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The document recommends using both clinical evaluation and various measurement methods to assess skin greasiness, considering factors like temperature and hormones.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.