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Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Aging-related hormone changes affect voice quality, especially during puberty, menstruation, pregnancy, and menopause.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Where a rhesus macaque used to live can affect its chances of getting alopecia later in life, and females are more likely to be affected than males.

PCOS in teen girls should be managed with lifestyle changes and sometimes medication to improve symptoms and health.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Testosterone is crucial for development, growth, and various body functions in mammals.

Hormonal status significantly affects women's skin health throughout their lives.

About 20% of Japanese macaques had head alopecia, and stress and environment might cause hair loss.

A lotion with minoxidil, hydrocortisone butyrate, and 17a-estradiol can improve or stabilize Frontal Fibrosing Alopecia in some cases, but there's no universally-accepted treatment yet.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Vegetarians should take B vitamin supplements to avoid health issues.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Moxibustion may help improve ovarian function by changing androgen levels.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

More research is needed to understand how testosterone is maintained in adult males.

High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.

Pregnancy can cause normal skin changes, including darkening of certain areas, nail changes, vascular changes, and breast changes like stretch marks.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Neurosteroids affect prolactin levels in sheep differently depending on stress and pregnancy conditions.

Monkeys with hair loss during pregnancy showed higher stress hormone levels and invested differently in their offspring.