November 2011 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” This study found that Polyomavirus A2 infection in mice led to the development of pilomatricomas in hair follicles, with the virus replicating initially in the skin and later infecting matrix cells.
In this case report, a 25-year-old woman with VKHD experienced an unusual occurrence of vellus-like hair growth on her normally hairless palm, observed twice over two years, expanding the known integumentary manifestations of VKHD.
January 2005 in “Journal of Cutaneous Pathology” This report presents the first known case of a proliferating hybrid cyst containing both epidermoid and trichilemmal components on the scrotum of a 44-year-old man.
1 citations
,
April 2023 in “Clinical, cosmetic and investigational dermatology” This study reviewed existing literature and reported two cases of perinevoid alopecia, suggesting that melanocyte antigens may be involved in its development.
October 2019 in “European Journal of Dermatology” This review discusses the diagnosis and treatment of pityriasis rubra pilaris and reports no new clinical results.
January 2022 in “Nasza Dermatologia Online” In this study, dermoscopy was suggested as a potentially useful tool for improving the clinical recognition of pilomatricoma.
42 citations
,
January 2003 in “International Journal of Gynecological Pathology” This research observed that multifocal pseudoepitheliomatous hyperplasia may explain some cases of squamous nests in vulvar lichen sclerosus with lichen simplex chronicus, potentially as a reaction to tissue damage rather than squamous cell carcinoma.
March 2009 in “Chinese Journal of Dermatology” This study observed that melanocytes in the outer root sheath of fetal scalp hair follicles may act as stem cells, showing rapid proliferation but immature function and morphology in culture.
November 2025 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” This study examined 16 sporadic trichoblastic tumors and found that although one showed malignant transformation, clinical follow-up revealed no residual or metastatic disease. RNA sequencing indicated a high tumor mutational burden and absence of a UV-related signature, helping to distinguish these tumors from similar growths.
September 2016 in “Journal of Dermatological Science” Polarizing light microscopy can easily and reliably diagnose congenital keratinizing disorders like Netherton syndrome.
October 2025 in “The Sri Lanka Journal of Dermatology” This case report highlights the diagnostic challenge of inverted follicular keratosis, emphasizing the importance of histopathology for accurate differentiation from malignancies.
26 citations
,
August 2014 in “Veterinary Dermatology” This study found that sphynx cats exhibit hair follicle dysplasia with abnormal hair shaft production, but without a reduction in the number of follicles, similar to murine KRT 71 mutants.
9 citations
,
May 2013 in “European Journal of Dermatology” This article discusses eruptive vellus hair cysts, describing their clinical characteristics, and reports no new research findings.
1 citations
,
May 2024 in “Dermatology Online Journal” In this case study, two middle-aged patients with pruritic scalp erosions were diagnosed with localized pemphigus vulgaris, which resolved without relapse after treatment with low-dose oral prednisone and intralesional triamcinolone acetonide.
5 citations
,
September 1986 in “Pediatric Dermatology” This study reported a previously undescribed form of hereditary hypotrichosis in a family, characterized by childhood-onset hair loss, morphea, and probable autosomal dominant inheritance.
August 2010 in “Journal of The American Academy of Dermatology” This educational activity reports no new research findings; it aims to help physicians assess and improve their clinical skills through self-evaluation and continued medical education.
1 citations
,
May 2023 in “Cureus” In this case report, a rare instance of pilomatrixoma was identified in the left hand of a 40-year-old patient, with successful surgical treatment and no recurrence observed after four years of follow-up.
This study observed that nevus melanocytes do not exhibit signs of senescence, suggesting that their growth arrest is due to cell interactions and not directly caused by BRAF activation.
1 citations
,
July 2009 in “Journal of dermatology” This case report describes a 29-year-old Japanese man with follicular mucinosis, suggesting nestin-positive, multipotent hair follicle stem cells may be involved in reticular epithelial degeneration of the outer root sheath.
8 citations
,
September 2016 in “The American Journal of Dermatopathology” This study found that eccrine duct dilation is significantly more frequent in cicatricial alopecias compared to noncicatricial alopecias, possibly due to the scarring process.
20 citations
,
February 2016 in “American Journal of Pathology” This study indicates that the OVOL1-OVOL2 axis may play a significant role in hair follicle differentiation and growth, potentially serving as therapeutic targets for hair disorders like alopecia and in the tumorigenesis of pilomatricoma.
A man's scalp hair loss was due to a combined melanocytic nevus and alopecia areata, suggesting a possible link between the two conditions.
June 2025 in “Journal of General-Procedural Dermatology & Venereology Indonesia” In this study, a 14-year-old boy with nevus sebaceous on his scalp underwent a three-stage serial excision, resulting in complete lesion removal with minimal scarring and no recurrence after six months.
4 citations
,
December 2014 in “Indian Journal of Dermatology” This case report documents a rare presentation of congenital milia en plaque on the scalp of a five-year-old boy, with blaschkoid extension to the nuchal area, highlighting its uncommon location and onset.
3 citations
,
January 1988 in “PubMed” This study found that scalp basal cell carcinomas do not appear to behave more aggressively than other types, despite suggestions in the literature.
16 citations
,
March 2011 in “Ophthalmic genetics” This case report documents a 63-year-old with Birt-Hogg-Dubé Syndrome who developed choroidal melanoma alongside multiple lid folliculomas, marking the first known association of these conditions.
7 citations
,
January 1990 in “Archives of Dermatological Research” Syringomas likely start in the upper dermis and form distinct luminal structures.
January 2026 in “Indian Journal of Ophthalmology - Case Reports” In this study, a rare case of a trichilemmal cyst in a 6-year-old's upper eyelid was observed; it was identified through histopathological examination after excision, highlighting the importance of considering trichilemmal cysts in atypical pediatric eyelid swellings.
18 citations
,
July 2016 in “Journal of The American Academy of Dermatology” This study reported that both primary and secondary cutaneous follicle center lymphomas can present with atypical scalp or forehead lesions, leading to potential misdiagnosis as other skin conditions.
14 citations
,
January 1998 in “Dermatology” This study found evidence that polythelia pilosa, previously excluded from classification, should be reintroduced as it marks true aberrant mammary structures in men and hirsute women.