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FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.

Fetal skin has unique immune cells different from adult skin.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.

MPA increases cancer spread by boosting Eph A2 activity.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

ADM scaffolds help skin heal by promoting a healing-type immune response.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.

A protein called MPZL3 in mitochondria slows down hair growth and could be a target for treating hair growth disorders.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

New treatments for immune disorders caused by FOXN1 deficiency are promising.

Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.

New hair regrowth model proposed, imiquimod found to kill skin cancer cells, T-cadherin loss linked to invasive skin cancer, no clear gene link to skin cancer after transplant, and study on children's hair loss shows male dominance and genetic ties.

The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.

New hair regrowth model introduced, imiquimod kills skin cancer cells, T-cadherin loss makes skin cancer more invasive, no strong link between PTCH1 gene and skin cancer after transplant, and male teens more likely to have hereditary hair loss.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.

A special hydrogel helps heal skin without scars and regrows hair.

Swiss Holstein cattle with curly, short hair carry genes from the Simmental breed.