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Early genetic testing and JAK inhibitors can help treat systemic inflammation in SAVI patients.

A new HRAS gene variant may cause a range of symptoms including intellectual disability and psychiatric issues.

A Jordanian family with Clouston syndrome has a common GJB6 gene mutation.

Scientists created a 3D skin model that shows typical signs of aging, which can help in aging research.

Anovulatory PCOS patients are younger with longer cycles and higher blood pressure and hormone levels.

A boy and his father with hereditary hypotrichosis simplex were treated for hair loss, but the treatment result is unknown.

Women with PCOS and androgenic alopecia have different triglyceride metabolism compared to those without hair loss.

Mutations in keratin genes cause skin disorders, but new treatments show promise.

Hair loss may indicate higher risk of heart disease.

Severe hair loss (androgenetic alopecia) is linked to higher risk of heart disease (cardiovascular atherosclerosis).

A specific gene mutation causes congenital hair loss.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

The unique coat of lykoi cats is likely caused by new variants in the Hairless gene.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.

Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.

Tridax procumbens shows potential for various health benefits but needs more scientific research.

Injecting triamcinolone into the eyebrow area may help eyelash regrowth in alopecia areata patients.

Transverse sections are better for non-scarring hair loss, vertical sections are better for lichen planopilaris, and either method works for other scarring hair loss types.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

The editor suggests removing "race" and "ethnicity" from dermatology and creating tools to objectively assess skin color and hair texture.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.