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The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Androgens may block hair growth signals, targeting this could treat hair loss.

About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Changing the amount of PLC5 in Arabidopsis affects root growth and drought resistance, with less PLC5 slowing root growth and more PLC5 improving drought tolerance but hindering root hair growth.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

A male with aromatase deficiency improved bone health with estradiol treatment.

Photobiomodulation may help with hair growth and wound healing, but research is inconsistent and needs better quality studies.

Losing eyelashes or eyebrows can be a sign of many different health problems and needs a careful approach to treat effectively.

The study found that women with PCOS have more and larger ovarian follicles and differences in ovarian structure, but these features alone can't always diagnose PCOS.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Minoxidil doesn't affect perifollicular lymphoid infiltration in alopecia areata patients.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

Loose anagen hair syndrome is caused by structural abnormalities in the hair follicle's inner root sheath.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.