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Activating TLR5 in the gut can extend lifespan and improve health in aged mice.

Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.

PCOS affects nearly 25% of female medical and dental students, impacting their academic and social lives.

Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Fetal skin has unique immune cells different from adult skin.

Forensic medicine is crucial for justice and needs continuous innovation and technology integration.

Human hair shows promise for non-invasive medical testing, but more research is needed to standardize its use.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Diuretics can cause serious side effects and should be used carefully.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

Understanding skin structure and development helps diagnose and treat skin disorders.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

Skin aging reflects overall body aging and can indicate internal health conditions.

Diagnosing alopecia areata is challenging and requires careful examination and various tests to distinguish it from other hair loss types.

Acupuncture may improve reproductive and metabolic functions in PCOS without negative side effects, but more research is needed to confirm its effectiveness.

Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.

Targeting drugs to hair follicles can treat skin conditions, but reaching deep follicle areas is hard and needs more research.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Better hair loss models needed for research.

Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.

Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.