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Clascoterone is safe for the heart, even at high doses.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

Gemcitabine and paclitaxel are effective and safe as first-line treatment for metastatic breast cancer.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

Sodium selenate was found to be safe and possibly slows Alzheimer's progression, but more research is needed.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.

2007 research improved understanding of prostate cancer risk, diagnosis, and treatment, but also showed the need for personalized treatment and further study on certain therapies' risks.

The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.

In 2007, prostate cancer research improved understanding of risk, diagnosis, and treatment, but also showed heart risks with certain therapies and the need for personalized care.

Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.

Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.

The document concludes that various treatments for skin conditions are effective, but some require further research, and certain factors like gender and lifestyle can influence disease outcomes.

Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.

Progesterone initially worsens but later reduces neuropathic pain in mice, through different mechanisms.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

The Scalp Coverage Scoring method reliably measures hair density from images.

Minoxidil not effective in preventing chemotherapy-induced hair loss.

Spironolactone and clascoterone are promising acne treatments with fewer side effects.

Henna has potential health benefits and can treat various conditions, but more research is needed to confirm safety and effectiveness.

Skin diseases are common and can significantly affect people's lives; better outcome measures and ethical clinical trials are needed to improve dermatology care.

Thuja orientalis hot water extract may help hair grow by starting the growth phase and improving hair follicle development.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Single-cell engineered biotherapeutics show promise for skin treatment but need more research and trials.

There are many treatments for common hair loss, but more trials are needed to decide which are best.