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The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

The conclusion is that androgen receptor gene polymorphism might be a marker for polycystic ovary syndrome, but more research is needed.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Low-dose oral minoxidil safely treats hair loss, with hypertrichosis as main side effect.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Finasteride shows promise for female hair loss, but more research needed.

Psychotropic medications can cause skin reactions, including severe conditions like SJS and TEN, and it's important for psychiatrists to recognize and manage these side effects.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Suppressing certain hormones might help prevent prostate cancer.