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LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Nerves and chemicals in the body can affect hair growth and loss.

Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.

Relatives of women with PCOS symptoms are more likely to have similar health issues.

Excessive body hair in women can be caused by various conditions and treated with medication like Diane® 35 or androgen blockers.

DNA methylation is essential for skin and hair follicle development, and could be a target for treating skin diseases.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stress can stop hair growth in mice, and treatments can reverse this effect.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Skin fat helps with body temperature control and has other active roles in health.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

HIV can cause unusual and severe skin problems that are hard to treat.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.

People with atopic dermatitis are more likely to develop other skin conditions due to shared genetics and immune pathways.

Some women with PCOS have CYP21 mutations and IRS1 variants, but these genetic factors are not major contributors to PCOS.

The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.

Ozone therapy might improve cancer treatment and reduce its side effects.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Low-dose anti-androgen drugs and certain drug combinations are effective for hirsutism, and insulin sensitizers show promise, especially for those with polycystic ovarian syndrome.

Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.