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Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

The true incidence of post-Finasteride syndrome is unclear, and more research is needed.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride may affect PNMT, causing side effects.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.