research Future Directions in the Treatment of Vitiligo
New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.
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510-540 / 1000+ results research Keratosis Pilaris With Adjacent Haemosiderin Deposition: A Clue to Scurvy
A man's skin condition and poor diet led to a scurvy diagnosis.
research Depigmentation Treatment for Vitiligo
Cryotherapy is the best depigmentation method for vitiligo but needs an expert to perform it.
research A Case of Scarring Alopecia
The woman was diagnosed with lichen planopilaris and can be treated with corticosteroids.
research San Francisco Dermatological Society: Case Studies of Vitiligo in Children
Ultraviolet light treatment with trioxsalen was ineffective for vitiligo in the cases described.
research Trichoscopy Update 2011
Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.
research Induction of Ornithine Decarboxylase in Specific Subpopulations of Murine Epidermal Cells Following Multiple Exposures to 12-O-Tetradecanoylphorbol-13-Acetate, Mezerein, and Ethyl Phenylpropriolate
The study investigated the effects of multiple exposures to 12-O-tetradecanoylphorbol-13-acetate (TPA), mezerein, and ethyl phenylpropriolate (EPP) on murine epidermal cells, focusing on the induction of ornithine decarboxylase (ODC) activity. While single applications of these agents caused similar hyperplasia and ODC induction, multiple treatments revealed significant differences in ODC activity, with TPA and mezerein inducing more than EPP. Immunocytochemical analysis showed distinct patterns of ODC-positive cells, with TPA prominently affecting perifollicular cells, mezerein affecting both interfollicular and perifollicular areas, and EPP affecting only interfollicular cells. Flow cytometry identified three keratinocyte subpopulations, with TPA causing the expansion of an intermediate-sized subpopulation not seen with EPP or mezerein. The findings suggested that TPA, a potent tumor promoter, selectively expanded a keratinocyte subpopulation hyperinducible for ODC, potentially important for neoplastic transformation, while mezerein and EPP were less effective in this regard.
research Alopecia Areata in a Rhesus Monkey (Macaca Mulatta)
The monkey's hair loss was due to an autoimmune disease, not genetics.
research Short-Term Biomarkers of Cigarette Smoke Condensate Tumor Promoting Potential in Mouse Skin
The study investigated the effects of cigarette smoke condensates (CSCs) on mouse skin, focusing on hyperplasia and inflammation as short-term biomarkers of tumor promotion. Using a truncated initiation-promotion protocol, the research assessed epidermal thickness, proliferative index, and ornithine decarboxylase (ODC) expression after CSC application. Results showed that CSCs increased these markers, with partial reversibility in interfollicular areas but sustained elevation in perifollicular regions. The study highlighted perifollicular ODC expression as a promising indicator for evaluating CSCs due to its rapid induction, low threshold, and potential to reflect irreversible changes, aligning with the notion that ODC expression is crucial for tumor promotion and that tumors primarily originate in the perifollicular epidermis.
research Nevus Comedonicus of the Scalp
A 10-year-old boy was diagnosed with a rare scalp condition causing hair loss and treated with a topical cream.
research Environmental Pathobiology of Frontal Fibrosing Alopecia: A Link Between Linalool Sensitization and FFA Development
Being allergic to linalool, a common fragrance ingredient, might contribute to developing frontal fibrosing alopecia.
research IL-15 Prolongs Hair Growth and Acts as a Guardian of Human Hair Follicle Immune Privilege
IL-15 helps maintain hair growth and protects the immune status of hair follicles.
research Clinical Pathological Observations and Animal Experimental Study of Trichotillomania Patients
Trichotillomania is more common in young females and often linked to stress and psychiatric conditions, with hair loss and increased catagen hair observed.
research The Effect of Autologous Activated Platelet Rich Plasma Injection on Pattern Hair Loss: Clinical and Histomorphometric Evaluation
AA-PRP injections effectively increase hair count and thickness for male pattern hair loss.
research Latest Understanding and Treatment of Alopecia Areata
New treatments for alopecia areata, like JAK inhibitors and immunomodulators, are promising.
research Calcitonin Gene-Related Peptide (CGRP) May Award Relative Protection from Interferon-γ-Induced Collapse of Human Hair Follicle Immune Privilege
CGRP may help protect hair follicles from immune system attacks, potentially slowing hair loss.
research Eosinophilic Pustular Folliculitis Involving Labial Mucosa, Which Improved with Naproxen
Naproxen effectively treated a girl's eosinophilic pustular folliculitis when other treatments failed.
research Patterned Hair Loss: A 47-Year-Old Man With Symmetrical Hair Loss and Itching Diagnosed With Fibrosing Alopecia in a Pattern Distribution
A 47-year-old man was diagnosed with a specific type of hair loss and advised to use certain medications and avoid hair transplants.
research New England Dermatological Society: A 37-Year-Old Woman with Pruritic Erythematous Lesion Leading to Scarring Alopecia
The woman's widespread skin condition did not improve despite various treatments.
research Balint’s Syndrome—Missed or Mistaken?
The document concludes that early diagnosis of Balint's syndrome is crucial for effective treatment and that understanding drug interactions, like between ritonavir and statins, is important for patient care.
research Angiogenin Is Expressed in Human Dermal Papilla Cells and Stimulates Hair Growth
Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
research Frontal Fibrosing Alopecia in Postmenopausal Women
Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.
research Lichen Planopilaris: Update on Diagnosis and Treatment
New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.
research Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review
No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.
research Folliculitis Decalvans: A Rare Inflammatory Scalp Disorder
Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.
research Frontal Fibrosing Alopecia: A Retrospective Review of 19 Patients Seen at Duke University
Dutasteride may help stabilize Frontal Fibrosing Alopecia, but more research is needed.
research Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component
Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.
research Frontal Fibrosing Alopecia Associated with Cutaneous Lichen Planus in a Premenopausal Woman
A premenopausal woman had hair loss and skin issues, treated with topical steroids.
research Female Pattern Hair Loss and Its Relationship to Permanent/Cicatricial Alopecia: A New Perspective
Some women with common hair loss may develop permanent hair loss.
research Folliculitis
Folliculitis is an inflammation of hair follicles that requires proper diagnosis and treatment based on the specific cause.