August 2025 in “International Journal of Environmental Sciences” In this descriptive cross-sectional study, researchers observed that less than 10% of female nursing students in Dharmapuri have been diagnosed with polycystic ovarian syndrome, though many show increasing symptom prevalence and poor health-related behaviors, underlining the need for better education and regular gynecological check-ups.
11 citations
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December 2013 in “Clinical and experimental dermatology” This study reports a case of a child with congenital skin fragility, alopecia, and cardiomyopathy due to compound heterozygous mutations in the DSP gene causing desmoplakin deficiency.
March 2026 in “Egyptian Journal of Forensic Sciences” This review critically examines Forensic DNA Phenotyping, highlighting high accuracy in predicting certain traits but also legal and ethical challenges, particularly around regulatory fragmentation and issues of genetic privacy.
In this study, latanoprost was found to stimulate VEGF protein synthesis in human dermal papilla cells, suggesting it may contribute to promoting hair growth.
297 citations
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December 2005 in “Journal of controlled release” This study found that POD-loaded solid lipid nanoparticles using 0.5% poloxamer 188 and 1.5% soybean lecithin (P-SLN) improved epidermal targeting and POD accumulation in porcine skin compared to traditional tincture.
2 citations
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February 2019 in “Journal of Investigative Dermatology” This study suggests that the expression of the DP2 receptor is higher in balding scalp cells and that its knockdown could inhibit the transition to the catagen phase in cultured human hair follicles, potentially counteracting hair growth inhibition associated with male pattern baldness.
11 citations
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October 2010 in “Behavioural Brain Research” This study found that neonatal administration of allopregnanolone enhances, while finasteride suppresses, the effects of adult intrahippocampal pregnenolone sulphate on rat locomotor activity in an open field test.
26 citations
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January 1992 in “Carcinogenesis” This study suggests that chronic treatment with TPA in mouse skin selectively expands a keratinocyte subpopulation hyperinducible for ODC, which may be a key target for neoplastic transformation.
12 citations
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August 2018 in “Psychiatry research” This study found that estazolam improved PTSD-like behavior deficits in an animal model, which was linked to increased allopregnanolone levels in specific brain regions.
65 citations
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February 2018 in “The Plant Journal” This study found that PLDζ2 and NPC4 enzymes play distinct roles in lipid remodeling and root hair growth in Arabidopsis under phosphate deficiency, influencing root hair density and length in a tissue- and time-specific manner.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this case study, a 26-year-old female with PLEC mutations and features of muscular dystrophy and myasthenia gravis showed significant improvement in symptoms following steroid treatment.
5 citations
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January 2016 in “Purdue e-Pubs (Purdue University System)” This study found that the welfare of dogs in commercial breeding facilities in Indiana was visualized as clean with minor foot health issues, and preventive care helped maintain good dental and ear health.
November 2023 in “The Journal of Urology” The conclusion is that future trials should report specific details about the PRP composition to better understand its effects on urologic conditions.
November 2025 in “The Journal of Sexual Medicine” This study found that the Mark Cuban Cost Plus Drug Company model offers substantial cost savings on men's health medications compared to Medicare and GoodRx, particularly for long-term treatments.
1 citations
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January 2013 This review explores the therapeutic applications of bimatoprost, including its role in glaucoma treatment, hair growth stimulation, and potential effects on fat deposition, but reports no new experimental findings.
36 citations
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June 2001 in “Neuroscience Letters” This study found that finasteride increased fetal arousal activity in late gestation sheep by suppressing pregnane steroid synthesis, suggesting reduced GABAA receptor-mediated inhibition.
July 2026 in “Frontiers in Endocrinology” This study observed that beef cattle with certain prolactin receptor gene mutations, known as slick mutations, demonstrated improved post-weaning growth and temperature regulation in a hot, humid climate compared to other genotypes, suggesting genotype influences growth efficiency and heat tolerance.
20 citations
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April 2023 in “The Journal of Urology” This study found that two injections of platelet-rich plasma were safe but no more effective than placebo in treating mild to moderate erectile dysfunction.
44 citations
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April 2012 in “BMB Reports” This study identified several DPC-specific proteins, including ITGB1, IGFBP3, and THBS1, as potential biomarkers for hair growth modulation through proteomic and network analysis.
March 2019 in “eCommons (Cornell University)” This report covers the diagnosis and treatment of equine pemphigus foliaceus presented by a case study of a Hackney pony mare, showing improvement with prednisolone treatment.
9 citations
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August 2023 in “Sexual Medicine Reviews” This review reports that while intracavernosal platelet-rich plasma is considered safe for treating erectile dysfunction, its efficacy remains unclear due to variable clinical trial protocols.
18 citations
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January 2021 in “Theranostics” This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.
31 citations
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July 2017 in “Journal of the American Academy of Dermatology” This study observed that apremilast treatment improved skin lesions and reduced pruritus in patients with chronic, severe atopic dermatitis and one case of hand and foot dermatitis.
180 citations
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June 2004 in “Journal of Pharmacology and Experimental Therapeutics” This study found that progesterone's antiseizure effects in mice occurred primarily through conversion to allopregnanolone, rather than through the progesterone receptor, as evidenced by results in PR knockout mice.
March 2008 in “European Urology Supplements” Finasteride and dutasteride can affect sexual function in BPH patients.
September 2024 in “Cermin Dunia Kedokteran” This source highlights the role of progestin in contraception, noting that while different types have varying progesteronic potential and effects, they share similar contraceptive mechanisms, allowing tailored use based on patient conditions.
3 citations
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February 2021 in “Experimental dermatology” This study observed that using 3D dermal papilla microtissues enhances hair follicle regeneration and gene expression compared to 2D cultures, indicating their potential for hair growth drug screening.
24 citations
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December 2012 in “Behavioural Brain Research” This study found that altering Allopregnanolone levels in neonatal rats affects their adult exploratory and anxiety-like behaviors and impairs avoidance learning.
48 citations
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February 1999 in “PubMed” This study found that the anticonvulsant effects of progesterone against PTZ-induced seizures in mice require conversion to allopregnanolone, as shown by the reversal of these effects with a 5alpha-reductase inhibitor.
14 citations
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October 2006 in “Journal of The American Academy of Dermatology” This report highlights a case where a woman's use of the dopamine agonist pramipexole for Parkinson's disease was associated with hair loss, which improved after discontinuing the drug.