October 2023 in “Recent Trends in Pharmaceutical Sciences and Research” This review examines the anatomy and physiology of hair, focusing on the hair growth cycle and various types of alopecia, using animal models such as mice and rats to study the condition's pathophysiology and aid in developing new treatments.
March 2017 in “The American Journal of Cosmetic Surgery” This case report suggests that transplanted hair follicles may be more resistant to alopecia areata than native hair, potentially offering new insights into the condition's pathophysiology and treatment options.
This review describes the link between obesity and gastrointestinal conditions, highlighting the need for more research to understand their pathophysiology and develop new treatments; it presents no new findings.
1 citations
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December 2022 in “Bioactive Materials” In this study, researchers developed a nanocomposite microneedle patch containing copper/zinc dual-doped silica nanoparticles, which release substances to promote hair follicle regeneration by targeting various pathophysiological aspects of androgenic alopecia, presenting an effective anti-hair loss treatment strategy.
October 2025 in “The American Journal of Gastroenterology” This report describes a case of SAPHO syndrome likely triggered by escalated dosing of infliximab in a 21-year-old woman, highlighting the complex nature of infliximab-induced adverse events, and suggesting a potential autoimmune basis involving two distinct pathophysiologies for SAPHO syndrome.
June 2024 in “Reviews on Recent Clinical Trials” This review analyzed current research on finasteride and dutasteride and found insufficient evidence to fully elucidate their role in metabolic adverse events, such as liver disease and diabetes, due to a lack of detailed pathophysiologic understanding; further studies are needed to clarify these mechanisms.
April 2021 in “Research Square (Research Square)” This case report describes significant improvements in both trichotillomania and bulimia symptoms with N-acetylcysteine treatment, suggesting a potential shared pathophysiological mechanism between the disorders.
January 2022 in “Social Science Research Network” This study demonstrates that a newly developed nanocomposite microneedle patch, releasing copper and zinc ions along with quercetin, effectively promotes hair follicle regeneration in androgenic alopecia by targeting various pathophysiological aspects of hair loss.
1 citations
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November 2024 in “Blood” This study found that inhibiting the PI3Kδ enzyme in murine models of cutaneous chronic graft-versus-host disease (cGVHD) reduced skin scores and fibrosis, prevented pathogenic lymphoid structures, and improved survival, suggesting it as a promising therapeutic approach to address the disease's hypoxic pathophysiology.
June 2026 in “kerbala journal of pharmaceutical sciences” In this case-control study, individuals with alopecia areata showed significantly elevated levels of inflammatory markers IL-4, IFN-γ, and CRP, as well as reduced serum Folate and Ferritin, suggesting the condition's multifactorial pathophysiology involves immune activation, systemic inflammation, and micronutrient deficiencies.
12 citations
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November 1993 in “International Journal of Dermatology” The document explains that hirsutism, often caused by hormonal issues, can be managed with treatment to improve both physical appearance and mental health.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
31 citations
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January 2020 in “Saudi Journal of Biological Sciences” This review examines how polymorphisms in androgen-related genes may influence genetic predisposition to PCOS but reports no consistent genetic marker.
11 citations
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September 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” Various treatments exist for hair loss, but more research is needed for better options.
January 2013 in “Dermatologic Clinics” Hair disorders need a holistic approach, including medical, cosmetic, and psychological support.
September 2004 in “PubMed” This article reviews the physiopathology, diagnosis, and treatment of androgenetic alopecia and reports no new findings; it emphasizes the importance of hormonal investigation and therapeutic evaluation.
7 citations
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December 2004 in “Medicine” This article reviews the anatomy and pathology of skin and hair to aid in diagnosing skin diseases and discusses potential therapies, without reporting new clinical results.
This review discusses the role of stem cells in the hair follicle bulge region for regenerative medicine and reports no new clinical results; the authors highlight the complexities in studying these cells' involvement in alopecia.
10 citations
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November 2017 in “Dermatologic clinics” This review discusses optimal cosmetic management for non-Caucasian men, emphasizing cultural and physiological considerations, but presents no new clinical findings.
January 2025 in “Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)” This study found a significant correlation between estradiol/testosterone imbalance and erectile dysfunction severity in Klinefelter syndrome patients, also highlighting high satisfaction with penile prosthesis in both psychogenic and organic cases.
January 2006 in “Yearbook of Dermatology and Dermatologic Surgery” Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
378 citations
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November 2011 in “Human reproduction update” This review discusses the epidemiology, causes, diagnosis, and management of hirsutism in women, noting that effective treatment requires addressing the root cause as well as the hair growth.
26 citations
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August 2016 in “Translational Andrology and Urology” This review discusses the impact of medical and surgical treatments for LUTS/BPH on ejaculatory function, highlighting that most treatments negatively affect it, except for some minimally invasive surgical therapies and specific medical therapies.
42 citations
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December 2007 in “American Journal of Psychiatry” This study examined finasteride, a 5-alpha-reductase inhibitor, for treating a Tourette’s syndrome patient unresponsive to traditional therapy, noting its limited side effects.
1 citations
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January 2010 in “Serbian Journal of Dermatology and Venereology” This article reviews the multifaceted approach required for acne vulgaris treatment, emphasizing individualized combination therapies tailored to clinical severity and patient psychological profiles, but no new results are included.
This study reviews female hair loss conditions with a focus on diagnosis and treatment. It highlights female pattern hair loss as the most common form and emphasizes the need for personalized therapy, including topical minoxidil and, when appropriate, antiandrogen treatments.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that both direct and witnessed trauma in mice were linked to lower levels of the neurosteroid allopregnanolone, and that boosting neurosteroidogenesis may alleviate PTSD-like symptoms, suggesting potential treatment strategies for PTSD stemming from either trauma type.
January 2019 in “ARC journal of pharmaceutical sciences” This review traces the historical understanding and treatment of acne across ancient Egyptian, Greek, and Roman civilizations, but provides no new clinical findings.
January 2023 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses pediatric androgenetic alopecia, emphasizing the diagnostic process and outlining potential treatments, but reports no new clinical results.
May 2019 in “Journal of the Dermatology Nurses’ Association” Folliculitis decalvans mainly affects middle-aged African American men and is treated with antibiotics.