22 citations
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December 2010 in “Journal of Cosmetic Dermatology” The authors concluded that finasteride treatment inhibits hippocampal neurogenesis in mice, potentially impacting emotional behaviors and contributing to the pathophysiology of affective disorders.
22 citations
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June 2010 in “Experimental Dermatology” This study reported that patients with alopecia areata have reduced expression of the melanocortin receptor MC2R in their scalp tissues compared to normal scalp, indicating potential involvement in the condition's pathophysiology.
18 citations
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October 2021 in “Frontiers in Physiology” This review summarizes recent research on the molecular properties and functions of L-PGDS and PGD2, but reports no new findings, highlighting their pathophysiological roles and guiding future studies.
10 citations
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March 2022 in “Communications biology” In this study, researchers found that non-invasive analysis of skin surface lipid RNAs revealed alterations in gene expression patterns associated with atopic dermatitis, suggesting its potential for understanding skin disease pathophysiology.
9 citations
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December 2017 in “The Journal of Allergy and Clinical Immunology” This review discusses the evolution of alopecia areata treatments towards more targeted therapies and reports no new clinical results, emphasizing cooperation between clinicians and scientists in understanding the disease's pathophysiology.
8 citations
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January 2024 in “Journal of Human Reproductive Sciences” This study found that serum zinc levels were lower in PCOS subjects compared to normal controls, suggesting zinc may play a vital role in PCOS pathophysiology.
8 citations
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August 2019 in “ACR Open Rheumatology” This review explores the biomechanical factors and signaling systems, like Wnt, involved in the pathophysiology of psoriatic nail lesions and reports no new results.
6 citations
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August 2024 in “Viruses” This review reported that despite identifying over 200 symptoms associated with long COVID, significant gaps and controversies remain in understanding its diagnosis, pathophysiology, risk factors, and the impact of viral strains and vaccination.
5 citations
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April 2024 in “ACS Chemical Neuroscience” This study developed and validated a highly sensitive method using ultrahigh-performance liquid chromatography with tandem mass spectrometry for accurately analyzing nine neuroactive steroids in human serum, which could enhance understanding of disease pathophysiology and support new biomarker and therapeutic discovery.
4 citations
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February 2022 in “International Journal of Molecular Sciences” This review discusses the similarities between myotonic dystrophy and aging, highlighting the role of cellular senescence in its pathophysiology, and reports no new clinical findings; the authors note potential anti-aging therapy applications.
3 citations
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April 2023 in “Journal of Veterinary Internal Medicine” This study found that dogs with idiopathic epilepsy had altered hair concentrations of several trace elements, which may suggest a role in the disease's pathophysiology and indicate effects from antiseizure medications.
3 citations
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January 2019 in “Case Reports in Ophthalmology” This case report describes a Japanese woman diagnosed with both Vogt-Koyanagi-Harada disease and sarcoidosis, suggesting a potential shared pathophysiology between the two conditions.
1 citations
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July 2023 in “Journal of Clinical Medicine” This review provides a detailed overview of the causes, prevalence, pathophysiology, clinical presentation, and treatment of beard alopecia, highlighting conditions such as alopecia areata, pseudofolliculitis barbae, and tinea barbae, and aims to serve as a resource for clinicians handling such cases.
1 citations
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January 2023 in “Metabolites” This review discusses the relationship between gut microbiota and polycystic ovarian syndrome (PCOS), including its potential mechanisms and the role of alterations in microbiome composition on PCOS pathophysiology.
April 2026 in “Expert Opinion on Biological Therapy” This review discusses prurigo nodularis and reports no new results, emphasizing the need for further research into its pathophysiology and treatment options.
January 2026 in “Advances in Clinical and Experimental Medicine” This paper proposes a model integrating regulatory T cells and mesenchymal stem/stromal cells to enhance understanding of peripheral immune tolerance, suggesting their combined roles in immune regulation, autoimmunity pathophysiology, and potential MSC-based therapies.
January 2026 in “Scientific Reports” This study found that among pediatric patients with alopecia areata, elevated eosinophilic hematological ratios were observed, suggesting these could serve as markers for disease exacerbation and the pathophysiology of the condition.
January 2026 in “Pharmaceutics” This review highlighted recent advances in nanocarrier-based topical delivery systems for skincare, emphasizing their potential to enhance ingredient stability, penetration, and targeted release while addressing specific pathophysiological skin concerns.
January 2026 in “Regenerative Biomaterials” This study highlights that hydrogel formulations unexpectedly prolonged healing in trials, pointing to a need for design based on detailed pathophysiological insights rather than empirical methods, and suggests technologies like AI materials optimization and 3D bioprinting to aid their clinical use for cancer survivors.
December 2025 in “AL-QADISIYAH MEDICAL JOURNAL” This study found that patients with alopecia areata had higher serum levels of interleukin-17 and interleukin-23 compared to healthy controls, suggesting these cytokines may play a role in the disease's pathophysiology.
December 2025 in “AL-QADISIYAH MEDICAL JOURNAL” The study conducted at Al-Diwaniya Teaching Hospital found that patients with alopecia areata exhibited significantly higher serum levels of interleukin-17 and interleukin-23 compared to healthy controls, suggesting these cytokines might play a role in the disease's pathophysiology.
October 2025 in “Progress In Microbes & Molecular Biology” This review reveals that PCOS is consistently linked to gut microbiota dysbiosis, characterized by reduced microbial diversity and shifts in composition, which are associated with various PCOS phenotypes and may present opportunities for microbiota-targeted therapies addressing the disorder's underlying pathophysiological mechanisms.
September 2025 in “Wound Repair and Regeneration” This review suggests that glucagon-like peptide 1 receptor agonists may play a potentially protective role in managing diabetic foot ulcers, particularly by addressing various underlying pathophysiological aspects.
August 2025 in “Indian Dermatology Online Journal” This review discusses how metaphorical language in dermatology, particularly terms like "butterfly" and "moth," aids in diagnosing and understanding skin conditions by highlighting their distinctive clinical presentations and underlying pathophysiology.
April 2025 in “Medical Journal of Babylon” This study found that male patients with alopecia areata had significantly higher levels of copeptin and cortisol compared to healthy controls, suggesting these biomarkers could play a role in the condition's pathophysiology and may serve as diagnostic indicators.
January 2025 in “Directory of Open access Books (OAPEN Foundation)” This review from "Dermatology - The Latest Research on Common Skin Diseases" compiles current scientific insights into common skin disorders, including their pathophysiology, symptoms, and emerging treatments, focusing on conditions like atopic dermatitis, vitiligo, and systemic scleroderma, which pose diagnostic and treatment challenges.
January 2025 in “Online Publication Service of Würzburg University (Würzburg University)” This study established a standardized in-vitro 3D skin model using adult diseased skin cells to investigate the underlying mechanisms of small fiber neuropathies, providing a foundation for further research into their pathophysiology.
October 2024 in “Journal of the Endocrine Society” This case study describes a 45-year-old man who developed post-finasteride syndrome with various symptoms after stopping Finasteride, highlighting the condition's rarity and poorly understood pathophysiology.
April 2024 in “Nigerian Postgraduate Medical Journal” This review summarizes existing knowledge on androgenetic alopecia, including its epidemiology, pathophysiology, and management, but presents no new research findings.
December 2023 in “Benha Journal of Applied Sciences” This study found that male patients with androgenetic alopecia had higher serum levels of Zinc Alpha 2 Glycoprotein than healthy controls, suggesting its potential role in the disease's pathophysiology.