January 2022 in “Social Science Research Network” This study demonstrates that a newly developed nanocomposite microneedle patch, releasing copper and zinc ions along with quercetin, effectively promotes hair follicle regeneration in androgenic alopecia by targeting various pathophysiological aspects of hair loss.
19 citations
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July 2019 in “Journal of Cosmetic Dermatology” This study found that in patients with patchy alopecia areata, certain trichoscopic features like upright regrowing hairs and pigtail hairs are positive predictive markers for treatment success.
1 citations
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February 2025 in “Journal of Drugs in Dermatology” This report describes two cases of cutaneous lupus erythematosus mimicking alopecia areata, highlighting the importance of considering CLE in the diagnosis of patchy hair loss to prevent scarring alopecia.
1 citations
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January 2019 in “Medical principles and practice” This case report describes a 17-year-old boy with alopecia areata who had vitamin D deficiency and an incidentally discovered adrenal ganglioneuroma, with alopecia receding after vitamin D supplementation but later recurring despite normalized vitamin D and no tumor return.
January 2026 in “Dermatology Online Journal” This case report highlights that CCCA can present with multifocal patchy hair loss in younger men of African descent, suggesting the need for careful evaluation when diagnosing atypical alopecia patterns.
4 citations
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September 2019 in “Biomedical Papers/Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic” This study found that CD2 could be a potential new therapeutic target for treating patchy-type alopecia areata, suggesting the need for further research into its role.
22 citations
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September 2024 in “Chemical Engineering Journal” A new microneedle patch effectively and safely treats alopecia areata.
3 citations
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May 2025 in “Carbohydrate Polymers” In this study, researchers developed a dissolvable microneedle patch containing baricitinib for alopecia areata treatment, reporting significantly higher hair growth in mouse models compared to controls, suggesting its potential as an effective, pain-free topical therapy.
September 2024 in “Archives of Dermatological Research” This study found that both red and green LED therapies combined with a microneedling patch significantly improved hair density and diameter in androgenetic alopecia patients over 24 weeks, with no serious side effects and similar efficacy between the two light wavelengths.
June 2024 in “Journal of the European Academy of Dermatology and Venereology” This abstract provides information on potential conflicts of interest and acknowledges sources of support for the findings, but does not report specific study results.
June 2023 in “JAAD Case Reports” This article reviews the epidemiology of desmoplastic melanoma and reports no new clinical findings, emphasizing higher risks in chronically sun-exposed older males.
March 2022 in “JAAD case reports” This case report highlights the importance of maintaining clinical suspicion for tinea incognito in patients with central centrifugal cicatricial alopecia who do not respond to typical corticosteroid treatments, as misdiagnosis can complicate treatment.
November 2025 in “Archives of Dermatological Research” Using a higher concentration of triamcinolone acetonide leads to faster hair regrowth in scalp patchy alopecia areata.
January 2024 in “Muller Journal of Medical Sciences and Research” This study found that trichoscopy was 73.77% concordant with histopathology in diagnosing patchy alopecia, highlighting its usefulness as a diagnostic tool for conditions like alopecia areata, lichen planus pigmentosus, and discoid lupus erythematosus.
34 citations
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June 2007 in “The Journal of Dermatology” This study observed that non-scarring diffuse hair loss was common in systemic lupus erythematosus patients, but did not find a significant relationship with the SLE Disease Activity Index.
30 citations
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October 2013 in “Lupus” This study identified distinct clinical and dermatoscopic features to differentiate non-scarring patchy alopecia in SLE from alopecia areata, emphasizing the value of serological tests in diagnosis.
3 citations
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December 2022 in “Rheumatology Advances in Practice” This case study reported that systemic lupus erythematosus (SLE) can initially present as patchy non-scarring alopecia, potentially misdiagnosed as alopecia areata, highlighting the importance of thorough examination.
In this study of 374 children with patchy hair loss in Delta Egypt, researchers found that most cases were due to non-scarring causes, particularly alopecia areata, followed by infectious causes like tinea capitis; these conditions were more prevalent in school-aged children from rural areas.
20 citations
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March 2019 in “Journal of The European Academy of Dermatology and Venereology” In this study, 5% minoxidil significantly improved outcomes for children and adults with patchy alopecia areata compared to placebo, with moderate quality evidence and no severe adverse events reported, though more research is needed to address remaining uncertainties.
1 citations
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June 2018 in “Archives of Disease in Childhood Education & Practice” In this case report, an adolescent girl with itchy alopecic patches showed hair regrowth and no new alopecia patches after 6 weeks of treatment, despite initial minimal improvement with oral doxycycline.
In this study on mice, a baricitinib-loaded microneedle patch enhanced hair growth in alopecia areata lesions (68% vs control: 33%, p < 0.05), suggesting it may deliver treatment effectively and pain-free, with fewer systemic side effects.
January 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” In this study, both fractional carbon dioxide laser therapy and cryotherapy were found to be effective and safe for treating patchy alopecia areata, showing similar efficacy in improving hair growth compared to untreated control patches.
January 2019 in “The Egyptian Journal of Hospital Medicine” In this study, researchers evaluated trichoscopic features in 500 Egyptian patients with patchy hair loss and found specific patterns, such as perifollicular scale with 90% sensitivity and 99.5% specificity, which effectively aid in diagnosing primary cicatricial alopecias.
November 2025 in “Bioscientia Medicina Journal of Biomedicine and Translational Research” In this case report, researchers describe a 44-year-old woman with refractory patch alopecia areata achieving complete hair regrowth using a multi-modal approach of systemic and topical cholecalciferol with microneedling, although systemic vitamin D repletion remains a significant confounder.
January 2026 in “BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY” In this randomized controlled trial, both Botulinum Toxin-A and Triamcinolone Acetonide showed substantial effectiveness in treating patchy Alopecia Areata, but Botulinum Toxin-A avoided complications while Triamcinolone led to skin atrophy in 16.7% of patients.
This article discusses the clinical features of tumid lupus erythematosus and emphasizes its importance as a differential diagnosis for noncicatricial alopecia, highlighting a case similar to alopecia areata without reporting new clinical results.
2 citations
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January 2022 in “Annals of Dermatology” This study found that treatment modalities and patch size influence hair regrowth patterns in alopecia areata patches.
June 2025 in “Archives of Dermatological Research”
October 2023 in “Research Square (Research Square)” In this study, researchers found that patients with new-onset mild alopecia areata had higher levels of oxidative stress markers and reduced antioxidant levels compared to healthy individuals, suggesting that oxidative stress might play a role in the condition.
This study observed that patients with new-onset mild alopecia areata had significantly higher levels of oxidative stress markers compared to healthy controls, suggesting their antioxidant defenses may be insufficient to balance the elevated oxidant levels.