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Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Apoptosis is essential for human skin development and forming a functional epidermis.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Sebocytes play a key role in controlling androgen levels in human skin.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Some medicinal plants can help heal wounds and may lead to new treatments.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.