349 citations
,
January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.
74 citations
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September 2003 in “The Journal of Immunology” This study found that PKCα activation in transgenic mice induces keratinocyte apoptosis and mediates neutrophilic skin inflammation via different pathways, suggesting potential mechanisms for cutaneous inflammatory diseases.
222 citations
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January 2005 in “Endocrine journal” This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.
1 citations
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January 2019 in “Journal of The Korean Institute of Illuminating and Electrical Installation Engineers” This study found that LEDs at specific wavelengths may improve antifungal performance and promote hair growth by activating scalp cells without inducing inflammation compared to a non-irradiated group.
February 2022 in “Authorea (Authorea)” This report presents a case of a seven-year-old girl with porokeratotic adnexal ostial nevus manifesting as hyperkeratotic verrucous papules on her left foot.
3 citations
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October 2013 in “Photodermatology Photoimmunology & Photomedicine” This study observed that combining targeted UVA phototherapy with topical 8-methoxypsoralen showed cosmetically acceptable hair regrowth in patients with patchy alopecia areata.
January 2026 in “Frontiers in Medicine” In this study, PP-PTKL exhibited antioxidant, anti-inflammatory, and pro-melanogenic effects in laboratory settings, suggesting its potential role in preventing or treating hair greying. Further animal and human studies are needed to verify these findings.
January 2024 in “Open MIND” This study will evaluate the potential of photobiomodulation, both alone and combined with melatonin supplementation, to promote hair regrowth in German Spitz dogs with alopecia X, by measuring hair follicle density and thickness over a 90-day period.
1 citations
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January 2025 in “Proceedings of the National Academy of Sciences” This study used cryoelectron microscopy to unveil the structure of LPA-bound human LPAR6, revealing unique ligand binding and recognition modes distinct from LPAR1, which may aid in designing targeted compounds for hair loss and cancer.
November 2023 in “Journal of the American Academy of Dermatology” This study explored spontaneous repigmentation after phenol-croton oil peels in skin of color, finding that temporary hypopigmentation resolved by day 21 in both a black-skin domestic pig model and human clinical observations, highlighting potential for these procedures despite past concerns about pigmentation issues.
10 citations
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September 2019 in “Experimental Eye Research” This review discusses the role of RDH12 in vision, its structural and functional aspects, and related disease mechanisms, but reports no new clinical results; it aims to support therapy development for inherited retinal dystrophies.
5 citations
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January 2010 in “International journal of trichology” This report describes two cases of alopecia totalis treated with turban psoralen and sunlight exposure, but it provides no clinical outcome results.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that p21 is much more highly expressed in normal melanocytes compared to melanoma cells, suggesting a potential target for preventing melanoma progression through cell cycle repair processes.
10 citations
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January 2010 in “Acta dermato-venereologica” Light therapy can effectively treat vitiligo and hair loss caused by a specific medication.
10 citations
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November 2009 in “Pigment cell & melanoma research” This study by Pérez-Oliva et al. explored how Mahogunin Ring Finger-1 (MGRN1) affects melanocortin-1 receptor (MC1R) signaling, suggesting that MGRN1 competitively inhibits Gαs binding to MC1R, influencing pigment production.
January 2023 in “Advances in reproductive sciences” This study found that women with PCOS and female androgenetic alopecia had significantly higher serum pannexin-1 channel levels compared to those without PCOS, suggesting a potential role in hair loss etiology.
16 citations
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January 2001 in “Clinical and Experimental Dermatology” Photodynamic therapy was effective in treating multiple scalp basal cell carcinomas with minimal side effects and good cosmetic results.
This study observed that, after 90 hours of light exposure, Finasteride retained 57% of its concentration, whereas Diclofenac and Naproxen retained only 12% and 9%, respectively.
70 citations
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December 2004 in “Proceedings of the National Academy of Sciences” This study found that BMP signaling influences hair pigmentation in mice by affecting the Agouti protein and interacts with MC-1R pathways to modulate melanin production.
8 citations
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January 2019 in “Journal of cosmetic dermatology” This study found that six sessions of a modified phenol peel effectively reduced hyperpigmentation in patients with Lichen Planus Pigmentosus, with 76% of treated individuals experiencing at least a 25% improvement, and no serious side effects reported.
July 1996 in “Clinical and Experimental Dermatology” This study found that a single topical application of calcipotriol ointment did not affect systemic calcium levels in patients with chronic plaque psoriasis.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that apocynin restored COL17A1 expression in human keratinocytes and reduced UVB-induced cellular senescence, DNA damage, and cell cycle arrest.
5 citations
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June 2016 in “JAMA Dermatology” This article highlights the limited photoprotection baseball caps provide against UV radiation and recommends additional sun protection measures, especially for those at risk of androgenetic alopecia, but reports no new results.
June 2021 in “Clinical neuropsychopharmacology and therapeutics” This paper reviews the hair color changes associated with valproic acid treatment, noting only a few reported instances of bleaching or darkening, and reports no new findings.
5 citations
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July 2014 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Latanoprost eye drops caused excessive hair growth and eyelash whitening in a woman.
September 2015 in “Photodiagnosis and Photodynamic Therapy”
1 citations
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January 2021 in “Dermatology online journal” This report describes a unique case of linear lichen planus pigmentosus on the face with histological features of lichen planopilaris, which has not been documented before.
1 citations
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December 2022 in “Exploration of Medicine” This review discusses the antioxidant and photoprotective potential of Polypodium leucotomos for use as a natural sunscreen ingredient and reports no new experimental results; further studies are recommended to evaluate its effectiveness.
53 citations
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July 1981 in “Journal of Endocrinology” In this study, α-MSH and cyclic AMP were found to stimulate melanogenesis in hair follicle cultures, while cyclic GMP and melatonin inhibited melanin production but not tyrosinase activity.
March 2013 in “Molecular & Cellular Toxicology/Molecular & cellular toxicology” In this study, exposure to m-Aminophenol in human keratinocytes altered the expression of thousands of genes involved in inflammation and stress responses, suggesting potential biomarkers for MAP-induced skin toxicity.