Modified Phenol Peels for Treatment-Refractory Hyperpigmentation of Lichen Planus Pigmentosus: A Retrospective Clinico-Dermoscopic Analysis

January 2019 in “ Journal of cosmetic dermatology ”

Sidharth Sonthalia, Maya Vedamurthy, Mary Ann Thomas, Mohamad Goldust, Abhijeet Kumar Jha, Sakshi Srivastava, Ishad Aggarwal

phenol peels Croton oil-free phenol combination hyperpigmentation Lichen Planus Pigmentosus LPP priming sun protection post-peel adjuvant topicals CFPC post-peel topicals

TLDR Modified phenol peels effectively reduced stubborn skin pigmentation in patients with Lichen Planus Pigmentosus.

The study analyzed the efficacy and safety of six sessions of Croton oil-free phenol combination (CFPC) peels for treating hyperpigmentation in 17 Indian patients with Lichen Planus Pigmentosus (LPP). Results showed that 5 patients (29%) experienced excellent improvement with over 75% reduction in pigmentation, while 13 patients (76%) had moderate to excellent improvement with at least 25% reduction. The treatment was well tolerated with no serious adverse effects. The study concluded that modified phenol peels were effective and safe for reducing LPP-associated hyperpigmentation, with thorough priming, stringent sun protection, and post-peel adjuvant topicals enhancing and maintaining the effects.

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