Modified Phenol Peels for Treatment-Refractory Hyperpigmentation of Lichen Planus Pigmentosus: A Retrospective Clinico-Dermoscopic Analysis

January 2019 in “ Journal of cosmetic dermatology ”

Sidharth Sonthalia, Maya Vedamurthy, Mary Ann Thomas, Mohamad Goldust, Abhijeet Kumar Jha, Sakshi Srivastava, Ishad Aggarwal

phenol peels Croton oil-free phenol combination hyperpigmentation Lichen Planus Pigmentosus LPP priming sun protection post-peel adjuvant topicals CFPC post-peel topicals

TLDR Modified phenol peels effectively reduced stubborn skin pigmentation in patients with Lichen Planus Pigmentosus.

The study analyzed the efficacy and safety of six sessions of Croton oil-free phenol combination (CFPC) peels for treating hyperpigmentation in 17 Indian patients with Lichen Planus Pigmentosus (LPP). Results showed that 5 patients (29%) experienced excellent improvement with over 75% reduction in pigmentation, while 13 patients (76%) had moderate to excellent improvement with at least 25% reduction. The treatment was well tolerated with no serious adverse effects. The study concluded that modified phenol peels were effective and safe for reducing LPP-associated hyperpigmentation, with thorough priming, stringent sun protection, and post-peel adjuvant topicals enhancing and maintaining the effects.

View this study on onlinelibrary.wiley.com →

Discuss this study in the Community →

Research cited in this study

2 / 2 results

research Lichen Planus Pigmentosus and Its Variants: Review and Update

94 citations , October 2017 in “International Journal of Dermatology”

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

research Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus: Is There a Link?

86 citations , July 2012 in “British journal of dermatology/British journal of dermatology, Supplement”

There may be a connection between Frontal Fibrosing Alopecia and Lichen Planus Pigmentosus, and more research is needed to confirm this.

Related Community Posts Join

6 / 10 results

community What is the consensus on topical tretinoin mono therapy?

in Research/Science 8 months ago

The conversation discusses the effectiveness of topical tretinoin as a monotherapy for hair loss, with users suggesting it may not be as effective as minoxidil or finasteride. The original poster is considering other options like a phenol peel and is concerned about the risks of derma rolling.

community Foods with sufficient procyanidin b2?

in Treatment 6 upvotes 4 years ago

Hair loss discussion includes treatments like Minoxidil, finasteride, and RU58841. Conversation focuses on foods with sufficient procyanidin b2, such as dark chocolate and apples, and the required dosage.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 743 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 11 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Help needed with finding an alternative to my dermatologist's recommendation ( shampoo and conditioner)

7 years ago

A user is seeking alternatives to **Curatio Triclenz Hair Cleanser** and **Triflow Hair Conditioner** due to issues with hair weight and scalp pimples. They need recommendations for mild shampoos available in Europe, preferably Sweden.

community PP405 Identity Research

in Research 292 upvotes 1 month ago

PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

Similar Research

5 / 1000+ results

research Common Dermatologic Procedures

9 citations , September 2015 in “Medical Clinics of North America”

The document explains how to do skin procedures, care after surgery, and when to use certain treatments.

research Cosmetic Dermatology Techniques for Photoaged Skin

2 citations , November 2014

Common cosmetic dermatology techniques improve skin damaged by the sun and aging.

research Facial Resurfacing of the Male Patient

8 citations , July 2008 in “Facial Plastic Surgery Clinics of North America”

More men are getting non-surgical cosmetic treatments due to increased income and social acceptance, with less invasive options being preferred.

research Aesthetic Dermatology Procedures During Coronavirus

13 citations , May 2020 in “Journal of Cosmetic Dermatology”

The article suggests using safety measures and telemedicine for aesthetic dermatology during COVID-19, while some procedures can still be done safely.

research Role and Mechanisms of Phytochemicals in Hair Growth and Health

2 citations , January 2023 in “Pharmaceuticals”

Natural products and phytochemicals may help with hair regrowth, but more research is needed.