Modified Phenol Peels for Treatment-Refractory Hyperpigmentation of Lichen Planus Pigmentosus: A Retrospective Clinico-Dermoscopic Analysis

    January 2019 in “ Journal of cosmetic dermatology ”
    Sidharth Sonthalia, Maya Vedamurthy, Mary Ann Thomas, Mohamad Goldust, Abhijeet Kumar Jha, Sakshi Srivastava, Ishad Aggarwal
    TLDR Modified phenol peels effectively reduced stubborn skin pigmentation in patients with Lichen Planus Pigmentosus.
    The study analyzed the efficacy and safety of six sessions of Croton oil-free phenol combination (CFPC) peels for treating hyperpigmentation in 17 Indian patients with Lichen Planus Pigmentosus (LPP). Results showed that 5 patients (29%) experienced excellent improvement with over 75% reduction in pigmentation, while 13 patients (76%) had moderate to excellent improvement with at least 25% reduction. The treatment was well tolerated with no serious adverse effects. The study concluded that modified phenol peels were effective and safe for reducing LPP-associated hyperpigmentation, with thorough priming, stringent sun protection, and post-peel adjuvant topicals enhancing and maintaining the effects.
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